【摘要】 目的 评估胃液荧光分析对早期胃癌诊断的价值。方法 收集54例放大胃镜诊断早期胃癌患者的胃液，用荧光胃液分析仪进行胃液荧光光谱检测；与对照组相比较。结果 以受试者工作特征(ROC)曲线为最佳截断点荧光胃液光谱(KJF)≥0.85为判断指标，诊断胃癌的灵敏度达92.0%，特异性为89.2%。结论 荧光胃液分析对胃癌的诊断是一种安全、有效的方法，对早期分化型胃癌的诊断有一定的特异性。

    【关键词】 胃液荧光分析;早期胃癌;胃液;放大胃镜

    A clinical study on fluorescence spectrum of gastric juice for early gastric cancer

    DONG Lin,WANG Tie-wu, SHI Ming-guo.Department of Digestion, The People’s Hospital of Ningxia , Yinchuan 750021, China

    【Abstract】 Objective To evaluate autofluorescence spectrum determination of gastric juice in clinical study for early gastric cancer. Methods A total number of 54 gastric juice specimens were collected from the patients underwent gastroscopy,then the fluorescence spectrums were detected using fluorescence spectrophotometer. Results Single analysis was carried out with SPSS software ,and the best critical point KJF≥0.85 on receive operate characteristic curve (ROC) was selected as diagnostic standard for gastric cancer. The sensitivity ,specificity of diluted gastric juice’s autofluorescence spectrum for diagnosing gastric cancer were 92.0%,89.2%. Conclusions Autofluorescence spectrum determination of gastric juice had safe and effective methods for clinical screening of early gastric cancer. ......