猫爪草多糖；_提取鉴别；_免疫功能；_环磷酰胺_

中药猫爪草多糖的免疫活性研究

http://www.100md.com 《时珍国医国药》 2007年第3期

猫爪草多糖；,提取鉴别；,免疫功能；,环磷酰胺,,猫爪草多糖；,提取鉴别；,免疫功能；,环磷酰胺,1器材,2方法[7~9],3讨论,参考文献：

     摘要：目的确定猫爪草多糖对实验动物免疫功能的影响。方法环磷酰胺造模法制作免疫抑制小鼠模型，灌胃给药，观察和比较猫爪草多糖对其腹腔巨噬细胞吞噬功能、溶血素形成以及外周血T淋巴细胞数的影响。结果猫爪草多糖可使吞噬百分率、吞噬指数显著升高；猫爪草多糖可显著促进溶血素的形成并提高外周血中T淋巴细胞数。结论猫爪草多糖对正常及免疫抑制小鼠均有免疫兴奋作用。

    关键词：猫爪草多糖；提取鉴别；免疫功能；环磷酰胺

    The Study About Immunocompetence of Polysaccharide of Radix Ranunculi Ternati

    ZHANG Zhenling, WANG Lei, WU Xiaojing, ZHANG Huixia

    (Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China)

    Abstract：ObjectiveTo investigate the influence of the polysaccharide on immune function.MethodsThe IS. model in Kunming mice was induced by Cyclophospharmude, and the phagoctosis of peritoneal macrophage, the formuation of hemoloysin and the number of T-lymphocytes in penpheral blood were observed.ResultsThe extract from Radix Ranunculi Ternati could elevate the percent and the index of phagocytosis, enhance the formation of the hemolysin obviously, and increase the number of T-lymphocytes in peripheral blood.ConclusionThe polysaccharide of Radix Ranunculi Ternati can stimulate the immunologic function of normal and IS. Kunming mice. ......

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