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危重创伤患者甲状腺功能正常性病变综合征的发生机制与诊治对策
http://www.100md.com 《创伤外科杂志》 2007年第2期
甲状腺;综合征;创伤;病理,,甲状腺;综合征;创伤;病理,关键词:甲状腺;综合征;创伤;病理,1发病机制,2临床表现,3诊断依据,4治疗对策,参考文献:
     摘要: 甲状腺功能正常性病变综合征(sick euthyroid syndrome,SES)在危重创伤患者中并不少见,严重者表现为颜面及全身肿胀,针眼可见持续的非血性液体流出,伤口渗液较多不易预期愈合,双侧胸腔积液或心包积液等。临床上常与液体复苏后的第三间隙液体潴留、低蛋白血症致胶体渗透压降低等的临床表现相混淆,很容易被忽略。其发病机制还不十分清楚,众多的研究首先考虑的致病因素是炎性因子。伴发SES会给创伤危重症的抢救带来一定的困难。是否给予积极地治疗仍存在某些争议,本文就其发病机制以及近年来的研究进展和临床治疗意见做一简介。

    关键词:甲状腺;综合征;创伤;病理

    Mechanism and treatment of sick euthyroid syndrome in critical trauma

    HU Peiqun,WANG Gi

    (ICU,Tianjin Hospital,Tianjin 300211,China)

    Abstract: Sick euthyroid syndrome(SES)should be often found in patients with critical trauma,but it is commonly confused SES with retention of fluid in third space after fluid resuscitation or with lowed colloid osmotic pressure as result of hypoproteinemia in the clinic.Serious SES is presented an edema of face and all over,nonblood fluid draining out of the needle hole,the wound not healing desiredly with fluid oozing unexpectedly,or pleural effusion on both sides,or pericardial effusion.The pathogenesis of SES is incompletely understood.The inflammatory cytokines are generally accepted as an important pathogenic factor of SES. Now,if the SES should be treated aggressively under dispute yet.However,the critical trauma patients rescued would be impeded by complication of SES.Recent progress in the research of SES mechanism and some opinions about the treatment of it are summarized here. ......

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