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复方红花滴丸的制备工艺研究
http://www.100md.com 《时珍国医国药》 2007年第3期
复方红花滴丸;,正交实验;,制备工艺,,复方红花滴丸;,正交实验;,制备工艺,1仪器与试药,2方法与结果,3讨论,参考文献:
     摘要:目的对复方红花滴丸的制备工艺进行考察。方法采用正交实验法研究成型的最佳工艺条件。结果以PEG6000作为基质,液体石蜡为冷却剂,药物与辅料以1∶5配比,料温70℃,滴口内外径1.2/1.3(内/外,mm/mm),滴距100 mm,滴速20滴/min,梯度冷却为最佳制备条件。结论 该工艺可为复方红花滴丸的制备提供实验依据。

    关键词:复方红花滴丸; 正交实验; 制备工艺

    Study on Preparation of Compound Safflower Dropping Pills

    YU Lian, ZHU Guangyi

    (Chemistry & Parmacy College of Jiamusi University, Jiamusi 154007, China)

    Abstract:ObjectiveTo study the preparation technology of Compound Safflower Dropping Pills. MethodsOrthogonal test was applied to optimize the preparation of Compound Safflower Dropping Pills.ResultsThe optimized project was as follow:the matrix contained PEG6000;the refrigerant was liquid paraffir,the rate of the drug to maxtrix was 1∶5 and the temperature of the drug was 70℃. The internal and external diameter of burette was 1.2mm and 1.3mm,respectively,the burette was 100mm above the surface of refrigerant, and the drug was dropped into Gradient cooling refrigerant at 20 drops per minute.ConclusionThe results provide the data for the ascertainment of shaping operation of Compound Safflower Dropping Pills at the manufacturing scale. ......

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