【摘要】 目的 探讨EMs组织中Survivin和PCNA表达的相关性及临床意义。方法 选取EMs患者异位内膜组织35份和在位内膜组织32份及正常子宫内膜组织26份，采用SP法测定Survivin和PCNA表达。结果 EMs异位和在位内膜组织中Survivin表达显著高于正常内膜组(P<0.05)，且异位内膜组Survivin表达也高于在位内膜(P<0.05)。EMs中Survivin表达阳性者的PCNA标记指数明显高于Survivin表达阴性者(P<0.05)。结论 Survivin在EMs发病机制中起重要作用且与细胞增殖相关。

    【关键词】 子宫内膜异位症；Survivin；PCNA；细胞增殖

    Expression and clinical significance of survivin and PCNA in endometriosis.

    LUO Xue-ying，WANG Zhan-ping.Department of Obstetrics and Gynecology，The First People’s Hospital of Shenyang，Shenyang 110041，China

    【Abstract】 Objective To explore the expression and clinical significance of survivin protein and PCNA in endometriosis.Methods Immunohistochemisty was used to determine the expression of survivin and PCNA in 35 cases of ectopic endometrial tissues，32 cases of eutopic endometrial tissues and 26 cases of normal endometrium.Results The expression of survivin in ectopic and eutopic endometrial tissues was much higher than that in normal endometrium(P<0.05) ......