Clinical effect of lianbai liquid in the prevention and treatment of irradiationª²induced dermal injury

    MA Hongª²Bing1, ZHANG Xiaoª²Zhi2, BAI Mingª²Hua1, WANG Xiª²Jing1

    1Department of Oncology, Second Affiliated Hospital, Xi¬ðan 710004, China, 2Department of Oncological Radiotherapy, First Affiliated Hospital, Medical College, Xi¬ðan Jiaotong University, Xi¬ðan 710061, China

    ¡¾Abstract¡¿ AIM: To observe the clinical effect of lianbai liquid in the prevention and treatment of irradiationª²induced acute dermal injury. METHODS: The carcinoma patients(n=126) who had to accept radiotherapy from May, 2000 to December,2005, were randomized into 2 groups :prevention group (n=75 ) was given lianbai liquid since the 1st radiotherapy session ,and control group 1 (n=51) was given only general and health education program without lianbai liquid application. Other 92 cases of 3ª²grade radiationª²induced dermatitis were randomly divided into 2 groups (n=54 in treatment group, n=38 in control group 2). The evaluation of radiationª²induced acute dermatitis was done according to CTC.V2.0 proposed by NCI. RESULTS: Skin reaction rate and grade in the prevention group(32.0%) was obviously lower than that of the control group 1 (92.2%) (u=6.769, P<0.01). The mild radiation reaction(1+2 grade)rate in the prevention group(28.0%) was obviously lower than that of the control group 1 (70.6%), with significant difference between the 2 groups (¦Ö2 =22.226, P<0.01). The effective rate of 3 grade acute radiationª²induced dermatitis in treatment group was 92.6%(50/54) ......