【摘要】 目的 分析浅表性膀胱癌患者行经尿道膀胱肿瘤电切术(TUR-Bt)后分别采用羟基喜树碱(HCPT)和卡介苗(BCG)进行膀胱灌注预防肿瘤复发的不同疗效。 方法 将64例浅表性膀胱癌术后患者随机分为两组，分别用HCPT、BCG作膀胱灌注治疗药物，观察其不同疗效。结果 所有病例随访12～24个月，平均16个月。HCPT组复发4(4/34)例，BCG组复发5(5/30)例，HCPT组复发率低于BCG组(P<0.05)，且副作用小。结论 羟基喜树碱疗效优于卡介苗，不良反应小，耐受性好，可以作为临床一线用药。

    【关键词】 膀胱癌；膀胱灌注；羟基喜树碱；卡介苗

    Compared observation of the effect of hydroxy camptothecin or BCG by bladder instillation to treat superficial bladder cancer on Prevention the recurrence after operation

    YAN Jun,YUAN Ya-guang.

    Department of Urologic Surgery,The Affiliated Hospital of Internal Mongolian Medical College,Huhehott 010050,China

    【Abstract】 Objective To evaluate the effect of HCPT and BCG by bladder instillation to treat superficial bladder cancer.Methods A total of 64 patients with superficial bladder cancer were divided into 2 groups randomly. HCPT by bladder instillation was used in the first group ......