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中华医学杂志930938Changes of circulating lymphocyte T3 receptors in diabetes mellitus Lu Guizhi, et al.First Teaching Hospital,Beijng Medical University,Beijing 100034
Using radioligand binding assay of receptors,westudied the changes of T3 receptors in circulating lymphocytes in 20 normal persons and 43 diabetic patients with or without low T3 .The mean value of serum T3 and FT3 was significantly decreased in all diabetic patients compared with that of normal controls.The concentration of serum T3 was negatively correlated with fasting blood glucose level. The serum rT3 was clearly increased in patients with low T3. The serum T4, FT4,FT4 I and TSH were normal in all patients The maximal binding capacity (MBC) of circulating lymphocyte T3 receptors which was negatively correlated with the seum T3 concentrations was obviously elevated in patients with diabetes mellitus. It was stil higher in patients with low T3 than in patients with normal T3,whereas the affinity of receptor was not changed.In conclusion,the increment of T3 receptor binding capacity reflects the compensatory mechanisms, whith are probably evoked by the T3 deficiency in order to maintain cellular homeostasis. ......
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中华医学杂志930938Changes of circulating lymphocyte T3 receptors in diabetes mellitus Lu Guizhi, et al.First Teaching Hospital,Beijng Medical University,Beijing 100034
Using radioligand binding assay of receptors,westudied the changes of T3 receptors in circulating lymphocytes in 20 normal persons and 43 diabetic patients with or without low T3 .The mean value of serum T3 and FT3 was significantly decreased in all diabetic patients compared with that of normal controls.The concentration of serum T3 was negatively correlated with fasting blood glucose level. The serum rT3 was clearly increased in patients with low T3. The serum T4, FT4,FT4 I and TSH were normal in all patients The maximal binding capacity (MBC) of circulating lymphocyte T3 receptors which was negatively correlated with the seum T3 concentrations was obviously elevated in patients with diabetes mellitus. It was stil higher in patients with low T3 than in patients with normal T3,whereas the affinity of receptor was not changed.In conclusion,the increment of T3 receptor binding capacity reflects the compensatory mechanisms, whith are probably evoked by the T3 deficiency in order to maintain cellular homeostasis. ......
您现在查看是摘要页，全文长 14938 字符。