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经皮冠状动脉腔内成形术早期结果对支架置入率的影响(摘要)
http://www.100md.com 《中国循环杂志》 1999年第0期
     作者:颜红兵 马长生 王勇 周玉杰

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    目的 目的:前瞻性评价经皮冠状动脉腔内成形术(PTCA)早期结果对支架置入率的影响。

    方法:1998年1月~1999年6月选择72例病人84处病变进行研究。男52例,女20例,平均年龄54.2岁。病人分为3组。A组(n=8):PTCA残余狭窄≤10%。B组(n=10):残余狭窄11%~25%。C组(n=54):残余狭窄≥25%或有夹层或急性闭塞。按标准方法行术前、术中和术后抗凝治疗和PTCA操作。A组和B组每隔10分作1次造影共3次,观察残余狭窄程度变化。若残余狭窄加重≥25%,则置入支架。C组直接置入支架。

    结果:A组8例10处病变中,A型病变6处,B1型病变3处,B2型病变1处。10分、20分造影,无残余狭窄加重≥25%。30分造影,1处B2型病变残狭窄加重≥25%。30分内残余狭窄程度加重≥25%的发生率为10%(1/10)。B组10例13处病变中,A型2处,B1型7处,B2型3处,C型病变1处。10分造影,无残余狭窄加重≥25%。20分造影,1处B2型病变残余狭窄加重≥25%。30分造影,1处C型病变残余狭窄加重≥25%。残余狭窄加重≥25%的发生率为16.7%(2/12)。C组54例61处病变中,A型病变3处,B1型病变14处,B2型病变27处,C型病变17处。
, 百拇医药
    结论:PTCA后支架样效果是指PTCA后残余狭窄≤10%或≤25%。若按前一标准(A组),PTCA即刻支架样结果仅为11.9%(10/84),30分后则降低到10.7%(9/84)。若按后一标准(A组+B组),支架样结果为27.4%(23/84),30分后则降低到23.8%(20/84)。结果说明,若按严格的标准,PTCA支架样结果约为10%,因而支架置入率非常高。

    Effect of Acute Result of Percutaneous Transluminal Coronary Angioplasty

    on a Stent Implantation Frequency (Abstract)

    Department of Cardiology, China-Japan Friendship Hospital, Beijing (100029)
, 百拇医药
    Yan Hongbing, Ma Changsheng, Wang Yong, et al.

    Objective: To determine the relationship of immediate outcome of percutaneous transluminal coronary angioplasty (PTCA) with a stent implantation frequency.

    Methods: Eighty-four coronary lesions in 72 patients during the period of January, 1998-June, 1999 were enrolled in this investigation. They were 52 males and 20 females with an average age of 54.2 years old. All patients were randomly divided into 3 groups. group A: ≤10% residual stenosis. group B: 11%~25% residual stenosis. group C: >25% residual stenosis, or dissections or acute closure. All patients underwent anticoagulation/ antiplatelet therapy before, during and after a PTCA procedure. All PTCA procedures were performed following the ACC/AHA guideline. In groups A and B, patients underwent a coronary angiography with an interval of 10 minutes for 3 times to follow up changes of the post-PTCA residual stenosis. And coronary stenting was indicated when ≥25% residual stenosis occurred. In group C, coronary stents were implanted without an angiographic follow-up.
, 百拇医药
    Results: in group A, 10 lesions in 8 patients include 6 type A lesions, 3 type B1 lesions and 1 type B2 lesion. No ≥25% residual stenosis was found on the 10 and 20 minute-after angiograms, but ≥25% residual stenosis was showed in 1 of type B1 lesions on the 30 minute-after angiogram with incidence of 10% (1/10). In group B, 13 lesions in 10 patients include 2 type A lesions, 7 type B1 lesions, 3 type B2 lesions and 1 type C lesion. No ≥25% residual stenosis was found on the 10 minute-after angiogram, but ≥25% residual stenosis was showed in one of type B2 lesions on the 20 minute-after angiogram and 1 type C lesion on the 30 minute-after angiogram with an incidence of 16.7% (2/12). In group C, 61 lesions in 54 patients include 3 type A lesions, 14 type B1 lesions, 27 type B2 lesions and 17 tyep C lesions.
, 百拇医药
    Conclusion: PTCA stent-like result is defined as a residual stenosis of ≤10% or of ≤25%. The present study showed that the stent-like result can be expected only in 11.9% (10/84) lesions immediately after a PTCA procedure, but in 10.7% (9/84) 30 minutes after when the former criteria was applied (group A). As showed in group B and group C, the stent-like result can be archived in 27.4% (23/84) lesions acutely after a PTCA procedure, but in 23.8% (23/84) 30 minutes after when the latter criteria was used. In a word, PTCA stent-like result can be expected only in 10% lesions after the procedure when a strict criteria was used and consequently a coronary stent implantation was carried out in a high percentage of patients., 百拇医药