镁与能量制剂对危重病人的临床意义
作者：石俊 南云泽
单位：延边大学医学院附属医院
关键词：
中国临床营养杂志000122摘 要：目的观察镁与能量(ATP-MgCl2)制剂对危重病人的临床意义。 方法通过对实验动物进行缺血损伤，应用MgCl2、ATP、ATP-MgCl2对肝、肾、心、肺等器官的作用，使用冷冻蚀刻、组织化学及原子吸收光谱等技术，并结合光镜、透射电镜观察损伤器官的超微结构与Mg2、ATP浓度变化的关系，探讨外源性镁及能量制剂对损伤修复的效果。 结果MgCl2、ATP两组对损伤器官均有保护作用(P>0.01)。而ATP-MgCl2组对损伤器官具有良好的保护作用(P<0.01)。该组细胞膜完整，胞质内有丰富糖原颗粒；质膜P面蛋白颗粒分布均匀，细胞核膜的P面上核孔分布均匀；细胞膜上、线粒体膜上及肌质网膜上均存在致密阳性产物，与正常组相近；原子吸收光谱显示线粒体内Qa2+明显下降。 结论将外源性ATP-MgCl2应用危重病人，取得良好疗效。
The clinical significance of mesuring serum Mg2+ and ATP for critical patient
SHI Jun ,NAN Yunze
(Affiliated Hospital of Yanbian University, College of Medicine)
Abstract：Objective To evaluate the effects of application of MgCI2, ATP, and ATP-MgCl2 on the funcrions of liver, kidney, heart and lung in experimontelly ischemic injuried animals, and to study the therapeutic role of exogenous Mg2+ and energy on repairmat of this injuny ming. Freeze etching, Histochemistry, Atomic Absorhtion Spectrum (AAS) and combine LM and EM. The experiment showed that MgCl2 and ATP protectived functions damnify organic (P>0.01) ,ATP-MgCl2 protected effect it notable results (P<0.01 ). Cell membrance was complete, glycogen became enriched in the cytoplasm, the uniform-distributed protein granule on Pside of plasma membtance of cell was found. There were positive material in the membrances and similar to normal group, cell michondia calcium decreased. Conclusions The exogenous application of ATP-MgCl was beneficial to the critical patient., 百拇医药
单位：延边大学医学院附属医院
关键词：
中国临床营养杂志000122摘 要：目的观察镁与能量(ATP-MgCl2)制剂对危重病人的临床意义。 方法通过对实验动物进行缺血损伤，应用MgCl2、ATP、ATP-MgCl2对肝、肾、心、肺等器官的作用，使用冷冻蚀刻、组织化学及原子吸收光谱等技术，并结合光镜、透射电镜观察损伤器官的超微结构与Mg2、ATP浓度变化的关系，探讨外源性镁及能量制剂对损伤修复的效果。 结果MgCl2、ATP两组对损伤器官均有保护作用(P>0.01)。而ATP-MgCl2组对损伤器官具有良好的保护作用(P<0.01)。该组细胞膜完整，胞质内有丰富糖原颗粒；质膜P面蛋白颗粒分布均匀，细胞核膜的P面上核孔分布均匀；细胞膜上、线粒体膜上及肌质网膜上均存在致密阳性产物，与正常组相近；原子吸收光谱显示线粒体内Qa2+明显下降。 结论将外源性ATP-MgCl2应用危重病人，取得良好疗效。
The clinical significance of mesuring serum Mg2+ and ATP for critical patient
SHI Jun ,NAN Yunze
(Affiliated Hospital of Yanbian University, College of Medicine)
Abstract：Objective To evaluate the effects of application of MgCI2, ATP, and ATP-MgCl2 on the funcrions of liver, kidney, heart and lung in experimontelly ischemic injuried animals, and to study the therapeutic role of exogenous Mg2+ and energy on repairmat of this injuny ming. Freeze etching, Histochemistry, Atomic Absorhtion Spectrum (AAS) and combine LM and EM. The experiment showed that MgCl2 and ATP protectived functions damnify organic (P>0.01) ,ATP-MgCl2 protected effect it notable results (P<0.01 ). Cell membrance was complete, glycogen became enriched in the cytoplasm, the uniform-distributed protein granule on Pside of plasma membtance of cell was found. There were positive material in the membrances and similar to normal group, cell michondia calcium decreased. Conclusions The exogenous application of ATP-MgCl was beneficial to the critical patient., 百拇医药