较长时间肠外营养支持病人加用生长激素的临床观察
作者：王宝贵 蒋朱明 王秀荣 张思源 于健春 马恩陵
单位：中国医学科学院 中国协和医科大学 北京协和医院基本外科
关键词：
中国临床营养杂志000120摘 要：目的观察重组人生长激素(rHGH)对较长时间接受肠外营养(PN)支持患者的影响。 方法16例患者接受传统肠外营养2周后，加用rHGH(8～12IU/d)2周。观察患者应用rHGH前后尿氮排出量和体重的变化。 结果患者在加用rHGH2周后较单纯接受传统肠外营养时体重有所增加(50.2±4.2kgvs52.3±4.3kg，P=0.01)；尿氮排出量在联合应用rHGH3天后明显减少(P=0.026)。重要脏器功能未见明显变化。 结论提示肠外营养支持联合应用rHGH可以增加患者体重，减少尿素氮排出量。
Effects of recombinant human growth hormone combined with relative longterm parenteral nutrition in G-I patients
WANG Baogui ,JIANG Zhuming ,WANG Xiurong
(PUMC Hospital ,Beijing)
Abstract：Objective Growth Hormone (GH) improves anabolism and cell proliferation. The purpose of this study was to observe the effect of recombinant human growth hormone (rHGH) combined with long team parenteral nutrition (PN) on nitrogen economy. Methods 16 patients were enrolled. Affter receiving solely PN (30 Kcal·kg-·d-) for 2 weeks, patients were treated by rHGH (8～12IU/d) with PN for 2 weeks. Resalts Showed the weight of patients increased after treatment of PN combined with rHGH, urine nitrogen significiantly decreased after combining rHGH 3 days. Conclusions These data had suggest that treatment of PN combine with rHGH results a increased patienb body weight and decreased urine nitragon., 百拇医药
单位：中国医学科学院 中国协和医科大学 北京协和医院基本外科
关键词：
中国临床营养杂志000120摘 要：目的观察重组人生长激素(rHGH)对较长时间接受肠外营养(PN)支持患者的影响。 方法16例患者接受传统肠外营养2周后，加用rHGH(8～12IU/d)2周。观察患者应用rHGH前后尿氮排出量和体重的变化。 结果患者在加用rHGH2周后较单纯接受传统肠外营养时体重有所增加(50.2±4.2kgvs52.3±4.3kg，P=0.01)；尿氮排出量在联合应用rHGH3天后明显减少(P=0.026)。重要脏器功能未见明显变化。 结论提示肠外营养支持联合应用rHGH可以增加患者体重，减少尿素氮排出量。
Effects of recombinant human growth hormone combined with relative longterm parenteral nutrition in G-I patients
WANG Baogui ,JIANG Zhuming ,WANG Xiurong
(PUMC Hospital ,Beijing)
Abstract：Objective Growth Hormone (GH) improves anabolism and cell proliferation. The purpose of this study was to observe the effect of recombinant human growth hormone (rHGH) combined with long team parenteral nutrition (PN) on nitrogen economy. Methods 16 patients were enrolled. Affter receiving solely PN (30 Kcal·kg-·d-) for 2 weeks, patients were treated by rHGH (8～12IU/d) with PN for 2 weeks. Resalts Showed the weight of patients increased after treatment of PN combined with rHGH, urine nitrogen significiantly decreased after combining rHGH 3 days. Conclusions These data had suggest that treatment of PN combine with rHGH results a increased patienb body weight and decreased urine nitragon., 百拇医药