磁力正畸与牙周组织中神经肽的研究进展
作者：常新 吕永利
单位：中国医科大学口腔医学院 沈阳110001
关键词：
解剖科学进展000208摘 要：SP和CGRP作为一级传入神经递质，广泛分布于周围神经系统，它们共同参与对感觉的调节。当外力作用于牙周组织时，会引起SP及CGRP的分布和密度的改变。本文将综述磁场的生物学效应和磁力在正畸中的应用进展，SP、CGRP的生物学特性、分布和作用以及正畸牙移动时牙周膜中SP与CGRP的变化。
参考文献：
[1]Sandier B. Magnetics and orthodontics. Br J orthod, 1989, 16(4): 243
[2]赵碧蓉.磁力矫治器在正畸中的应用.国外医学口腔医学分册，1981, 8(1)：38
, 百拇医药
[3]Kawata J. A new orthodontic force system of magnetic brackets. Am J orthod Demi fac orthop, 1987, 92: 241
[4]Linder-Aronson A, Lindskog S. The skeletal and dental effects of rapid maxillary expansion. Swed Dent J, 1995, 19(4): 131
[5]Zhao gui-zhi. Effects of permanent magnetic field on DNA metabolism of human periodontal ligament fihrohlasts in vitro.Chung Hua Kou Chiang Hsueh Tsa Chih, 1994, 29(2): 75
, 百拇医药
[6]Wilson BW, Matt KS, Morris JE, et al. Effects of 60Hz magnetic field exposure on the pineal and hypothalamic-pituitarygonadal axis in the siberian hamster. Bioelectro magnetics,1999, 20(4): 224
[7]Akerstedt T, Arnetz B, Ficca G, et al. A 50Hz electro-magnetic field impairs sleep. J sleep Res, 1999, 8(1): 77
[8]Burchard JF, Nguyen PH, Richard L, et al. Effects of electro magnetic fields on the levels of biogenic amine metabolites,quinolinic acid and beta-endorphin in the cerebrospinal fluid of dairy cows. Neurochem Res, 1998, 23(12): 1527
, 百拇医药
[9]Blechman AM. Magnetic force in orthodontics. Am J orthod,1978, 14: 435
[10]Blechman AM. Magnetic force system in orthodontics. Am J orthod, 1985, 87:201
[11]Alexander DV. Magnetic versus mechanical expansion with different force threshold and points of force appliance. Am J orthod Denti fac orthop, 1987, 92(6): 455
[12]Alexander DV. Stability of magnetic versus mechanical palatal expansion. Eur J orthod, 1989, 11:107
, 百拇医药
[13]Dellinger EL. A clinical assessment of the active vertical correction -A nonsurgical alternative for skeletal open bite treatment. Am J orthod, 1986, 89(5): 428
[14]华晓鹰.感觉神经之中的神经肽及其有关的外周功难.生理科学进展，1988，13：304
[15]Wakisaka S, Ichikawa H. Substance P-like immunoreactivity in the pulp-dentine zone of human molar teeth demonstrated by indirect immunofluorescence method. Arch oral Biol, 1984, 29:73
, 百拇医药
[16]吴康.降钙素基因相关肽的研究.生理科学进展，1989，20：57
[17]Byets MR, Taylor PE, Khayat BG, et al. Effects of injury and inflammation on pulpal and periapical nerve. J Endod, 1990,16:78
[18]Karin 3, Heyeraas H, lnger K, et al. Nerve fibers immunoreactive to protein gene product 9. 5, calcitonin gene-related peptide, substance P and neuropeptide Y in the dental pulp, periodontal ligament and gingiva in cats. Acta Opontol Scand,1993, 51:206
, 百拇医药
[19]Wakisaka S, Ichikawa H, Nishikawa S, et al. The distribution and origin of substance P-like immunoreactivity in the rat molar pulp and periodontal tissues. Arch oral Biol, 1985, 30 (11-12): 813
[20]Davidovitch Z, Nicolayo F, Ngan PW, et al. Neurotransmitters, cytokines and the control of alveolor bone remodeling in orthodontics. Dental clinics of north America, 1988, 32:411
[21]Foreman JC. Substance P and calcitonin gene-related peptide: Effects on most cells and in human skin. International Archives of Allergy Applied Immunology, 1987, 48:366
, http://www.100md.com
[22]Kvinnsland I. Effect on traumatic occlusion on CGRP and SP immunoreactive nerve fiber morphology in rat molar pulp and periodontium. Histochemistry, 1992, 97: 111
[23]Saito J, Ishii K, Hanada K, et al. Responses of calcitonin gene-related peptide-immunopositive nerve fibers in the periodontal ligament of rat molars to experimental tooth movement. Archives of oral Biology, 1991, 36:889
[24]Nagata E, Kondo T, Ayasaka N, et al. Immunohistochemical study of nerve fibers with substance P or calcitonin gene-related peptide-like immunoreactivity in the junctional epithelium of developing rats. Archives of oral Biology, 1002, 37:655, 百拇医药
单位：中国医科大学口腔医学院 沈阳110001
关键词：
解剖科学进展000208摘 要：SP和CGRP作为一级传入神经递质，广泛分布于周围神经系统，它们共同参与对感觉的调节。当外力作用于牙周组织时，会引起SP及CGRP的分布和密度的改变。本文将综述磁场的生物学效应和磁力在正畸中的应用进展，SP、CGRP的生物学特性、分布和作用以及正畸牙移动时牙周膜中SP与CGRP的变化。
参考文献：
[1]Sandier B. Magnetics and orthodontics. Br J orthod, 1989, 16(4): 243
[2]赵碧蓉.磁力矫治器在正畸中的应用.国外医学口腔医学分册，1981, 8(1)：38
, 百拇医药
[3]Kawata J. A new orthodontic force system of magnetic brackets. Am J orthod Demi fac orthop, 1987, 92: 241
[4]Linder-Aronson A, Lindskog S. The skeletal and dental effects of rapid maxillary expansion. Swed Dent J, 1995, 19(4): 131
[5]Zhao gui-zhi. Effects of permanent magnetic field on DNA metabolism of human periodontal ligament fihrohlasts in vitro.Chung Hua Kou Chiang Hsueh Tsa Chih, 1994, 29(2): 75
, 百拇医药
[6]Wilson BW, Matt KS, Morris JE, et al. Effects of 60Hz magnetic field exposure on the pineal and hypothalamic-pituitarygonadal axis in the siberian hamster. Bioelectro magnetics,1999, 20(4): 224
[7]Akerstedt T, Arnetz B, Ficca G, et al. A 50Hz electro-magnetic field impairs sleep. J sleep Res, 1999, 8(1): 77
[8]Burchard JF, Nguyen PH, Richard L, et al. Effects of electro magnetic fields on the levels of biogenic amine metabolites,quinolinic acid and beta-endorphin in the cerebrospinal fluid of dairy cows. Neurochem Res, 1998, 23(12): 1527
, 百拇医药
[9]Blechman AM. Magnetic force in orthodontics. Am J orthod,1978, 14: 435
[10]Blechman AM. Magnetic force system in orthodontics. Am J orthod, 1985, 87:201
[11]Alexander DV. Magnetic versus mechanical expansion with different force threshold and points of force appliance. Am J orthod Denti fac orthop, 1987, 92(6): 455
[12]Alexander DV. Stability of magnetic versus mechanical palatal expansion. Eur J orthod, 1989, 11:107
, 百拇医药
[13]Dellinger EL. A clinical assessment of the active vertical correction -A nonsurgical alternative for skeletal open bite treatment. Am J orthod, 1986, 89(5): 428
[14]华晓鹰.感觉神经之中的神经肽及其有关的外周功难.生理科学进展，1988，13：304
[15]Wakisaka S, Ichikawa H. Substance P-like immunoreactivity in the pulp-dentine zone of human molar teeth demonstrated by indirect immunofluorescence method. Arch oral Biol, 1984, 29:73
, 百拇医药
[16]吴康.降钙素基因相关肽的研究.生理科学进展，1989，20：57
[17]Byets MR, Taylor PE, Khayat BG, et al. Effects of injury and inflammation on pulpal and periapical nerve. J Endod, 1990,16:78
[18]Karin 3, Heyeraas H, lnger K, et al. Nerve fibers immunoreactive to protein gene product 9. 5, calcitonin gene-related peptide, substance P and neuropeptide Y in the dental pulp, periodontal ligament and gingiva in cats. Acta Opontol Scand,1993, 51:206
, 百拇医药
[19]Wakisaka S, Ichikawa H, Nishikawa S, et al. The distribution and origin of substance P-like immunoreactivity in the rat molar pulp and periodontal tissues. Arch oral Biol, 1985, 30 (11-12): 813
[20]Davidovitch Z, Nicolayo F, Ngan PW, et al. Neurotransmitters, cytokines and the control of alveolor bone remodeling in orthodontics. Dental clinics of north America, 1988, 32:411
[21]Foreman JC. Substance P and calcitonin gene-related peptide: Effects on most cells and in human skin. International Archives of Allergy Applied Immunology, 1987, 48:366
, http://www.100md.com
[22]Kvinnsland I. Effect on traumatic occlusion on CGRP and SP immunoreactive nerve fiber morphology in rat molar pulp and periodontium. Histochemistry, 1992, 97: 111
[23]Saito J, Ishii K, Hanada K, et al. Responses of calcitonin gene-related peptide-immunopositive nerve fibers in the periodontal ligament of rat molars to experimental tooth movement. Archives of oral Biology, 1991, 36:889
[24]Nagata E, Kondo T, Ayasaka N, et al. Immunohistochemical study of nerve fibers with substance P or calcitonin gene-related peptide-like immunoreactivity in the junctional epithelium of developing rats. Archives of oral Biology, 1002, 37:655, 百拇医药