王峰 娜斯曼·尼加提 段丽 倪瓒

    【摘要】目的 探討儿童原发性免疫性血小板减少症(ITP) 与年龄相关的临床特点。 方法 回顾性分析257例ITP患儿的临床资料，对 3岁组的性别、发病季节、发病诱因、出血情况、初诊时血小板参数、治疗方法、疗效及预后情况进行统计学分析。 结果 ①257例患儿中 3岁69例(26.9%)。 3岁组发病有明显的季节性，而1 ～ 3岁组各季节持平。> 3岁组与其他2组发病季节比较差异有统计学意义(P均 3岁组鼻出血比例较高，3组间出血情况比较差异均有统计学意义(P均 3岁组后两者明显升高(P均 3岁组IVIG联用激素的比例更高(P均 3岁患儿的MPV与PDW明显升高。3 year-old groups. Results Among 257 children， 118 cases (45.9%) were aged 3 years. The male-to-female ratio in the 3 year-old groups was pronounced， whereas the incidence of ITP was almost the same throughout the year in the 1-3 year-old group. There was a significant difference in the onset season between the > 3 year-old group and the other two groups (both P 3 year-old group. There was a significant difference in bleeding among three groups (all P 3 year-old group (both P 3 year-old group was the highest (all P 3 years. The complete response rate is the highest and the proportion of chronic ITP is the lowest in the 12个月)14例 ......