[摘 要]目的：从基因转录水平分析针刺腧穴和非腧穴效应的差异。方法：选取健康、雄性7月龄快速老化模型鼠(SenescenceAcceleratedMouse，SAM-P/10)。随机分为非针刺组、穴位针刺组和非穴位针刺组，每组20只，采用DDRT-PCR技术，展示三组脑基因表达谱的变化情况。结果：针刺腧穴可引起某些基因表达的增强，而非穴则没有明显的变化，同时观察到针刺非穴可以引起一定的应激反应。结论：腧穴具有一定的特异性，临床上应准确取穴以增强疗效。

    [主题词]穴位特异性；基因表达；针刺感应

    AnalysisonDifferenceofAcupunctureEffectsBetweenAcupointandNon-AcupointfromDiffe

    renceofGeneExpression

    YuJianchun，YuTao，HanJingxian(DepartmentofGerontology，theFirstAffiliatedHospital，TianjinCollegeofTCM，Tianjin300193，China)

    [Abstract]PurposeToanalyzedifferenceofacupunctureeffectsbetweenacupointandnon-a

    cupointingenetictran-scriptionlevel.Methods Healthy，malesenescenceacceleratedmice，SAM-P/10，aged7months，weredividedrandom-lyintonon-acupuncturegroup，acupointacupuncturegroupandnon-acupointacupuncturegroup ......