胰岛素受体底物的功能及其基因多态性与2型糖尿病的关系(7)
[29] CELI FS，NEGRI C，TANNER K，et al. Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with type 2 diabetes mellitus[J]. Diabetes Metab Res Rev，2000，16(5)：370- 377.
[30] ORKUNOGLU SUER FE，MERGEN H，BOLU E，et al. Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Turkish with type 2 diabetes mellitus[J]. Endocr J，2005，52(5)：593-598.
[31] WANG H，RISSANEN J，MIETTINEN R，et al. New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes[J]. Diabetes，2001，50(8)：1949-1951.
[32] BODHINI D，RADHA V，DEEPA R，et al. The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians[J]. Int J Obes (Lond)，2007，31(1)：97-102.
[33] OKAZAWA K，YOSHIMASA Y，MIYAMOTO Y，et al. The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes[J]. Diabetes Res Clin Pract，2005，68(1)：39-48.
[34] 孔令芳，赵彦艳，李强，等. IRS2基因G1057D变异与中国汉族人肥胖型2型糖尿病的相关性[J].中华医学遗传学杂志，2005，22(4)：387-390.
[35] OUEDERNI TB，SANCHEZ-CORONA J，FLORES MA- RTINEZ SE，et al. The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population[J]. Clin Biochem，2009，42(10/11)：1169-1173.
[36] MELKERSSON K，PERSSON B. Association between body mass index and insulin receptor substrate-4 (IRS-4) gene polymorphisms in patients with schizophrenia[J]. Neuro Endocrinol Lett，2011，32(5)：634-640.
[37] MELKERSSON K，PERSSON B. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene[J]. Neuro Endocrinol Lett，2012，33(3)：321-330.
[38] IDF. IDF diabetes atlas-8th edition[EB/OL]. [2017-12- 01].http：//www.diabetesatlas.org/resources/2017-atlas.html.
(收稿日期：2017-04-21 修回日期：2017-12-15)
(編辑：余庆华), 百拇医药(孙加琳 荆凡波 徐文 全香花 李晓 郭切 李欣 隋忠国)
[30] ORKUNOGLU SUER FE，MERGEN H，BOLU E，et al. Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Turkish with type 2 diabetes mellitus[J]. Endocr J，2005，52(5)：593-598.
[31] WANG H，RISSANEN J，MIETTINEN R，et al. New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes[J]. Diabetes，2001，50(8)：1949-1951.
[32] BODHINI D，RADHA V，DEEPA R，et al. The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians[J]. Int J Obes (Lond)，2007，31(1)：97-102.
[33] OKAZAWA K，YOSHIMASA Y，MIYAMOTO Y，et al. The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes[J]. Diabetes Res Clin Pract，2005，68(1)：39-48.
[34] 孔令芳，赵彦艳，李强，等. IRS2基因G1057D变异与中国汉族人肥胖型2型糖尿病的相关性[J].中华医学遗传学杂志，2005，22(4)：387-390.
[35] OUEDERNI TB，SANCHEZ-CORONA J，FLORES MA- RTINEZ SE，et al. The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population[J]. Clin Biochem，2009，42(10/11)：1169-1173.
[36] MELKERSSON K，PERSSON B. Association between body mass index and insulin receptor substrate-4 (IRS-4) gene polymorphisms in patients with schizophrenia[J]. Neuro Endocrinol Lett，2011，32(5)：634-640.
[37] MELKERSSON K，PERSSON B. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene[J]. Neuro Endocrinol Lett，2012，33(3)：321-330.
[38] IDF. IDF diabetes atlas-8th edition[EB/OL]. [2017-12- 01].http：//www.diabetesatlas.org/resources/2017-atlas.html.
(收稿日期：2017-04-21 修回日期：2017-12-15)
(編辑：余庆华), 百拇医药(孙加琳 荆凡波 徐文 全香花 李晓 郭切 李欣 隋忠国)