纳米载药系统应用于缺血性脑卒中的研究进展(4)
[ 4 ] ZHENG S，BAI YY，LIU Y，et al. Salvaging brain ischemia by increasing neuroprotectant uptake via nanoagonist mediated blood brain barrier permeability enhancement[J]. Biomaterials，2015，66：9-20.
[ 5 ] BANKS WA. From blood-brain barrier to blood-brain interface：new opportunities for CNS drug delivery[J]. Nat Rev Drug Discov，2016，15(4)：275-292.
[ 6 ] LI X，TSIBOUKLIS J，WENG T，et al. Nano carriers for drug transport across the blood-brain barrier[J]. J Drug Target，2017，25(1)：17-28.
, 百拇医药
[ 7 ] CHEN Z，ZHAI M，XIE X，et al. Apoferritin nanocage for brain targeted doxorubicin delivery[J]. Mol Pharm，2017，14(9)：3087-3097.
[ 8 ] AGULLA J，BREA D，CAMPOS F，et al. In vivo theranostics at the peri-infarct region in cerebral ischemia[J].Theranostics，2013，4(1)：90-105.
[ 9 ] GR?NBERG NV，JOHANSEN FF，KRISTIANSEN U，et al.Leukocyte infiltration in experimental stroke[J]. J Neuroinflammation，2013，10(1)：115.
, 百拇医药
[10] KIM JY，KAWABORI M，YENARI MA. Innate inflammatory responses in stroke：mechanisms and potential therapeutic targets[J]. Curr Med Chem，2014，21(18)：2076-2097.
[11] RODRIGO R，FERN?NDEZ-GAJARDO R，GUTI?RREZ R，et al. Oxidative stress and pathophysiology of ischemic stroke：novel therapeutic opportunities[J].CNS & Neurol Disord Drug Targets，2013，12(5)：698-714.
[12] HUANG J，UPADHYAY UM，TAMARGO RJ. Inflammation in stroke and focal cerebral ischemia[J].Surgical neurology，2006，66(3)：232-245.
, http://www.100md.com
[13] MOQIN AA. Disruption of ionic and cell volume homeostasis in cerebral ischemia： the perfect storm[J]. Pathophysiology，2007，14(3/4)：183-193.
[14] BOND? ML，DI GES? R，CRAPARO EF. Lipid nanoparticles for drug targeting to the brain[J]. Method Enzymol，2012，508：229-251.
[15] SONALI S，SINGH RP，SINGH N，et al. Transferrin liposomes of docetaxel for brain-targeted cancer applications：formulation and brain theranostics[J]. Drug Deliv，2016，23(4)：1261-1271.
, 百拇医药
[16] SHIMBO D，ABUMIYA T，SHICHINOHE H，et al.Post- ischemic intra-arterial infusion of liposome-encapsulated hemoglobin can reduce ischemia reperfusion injury[J]. Brain Res，2014，1554：59-66.
[17] ISHII T，ASAI T，OYAMA D，et al. Treatment of cerebral ischemia-reperfusion injury with PEGylated liposomes encapsulating FK506[J]. FASEB J，2013，27(4)：1362-1370.
[18] NICHOL A，FRENCH C，LITTLE L，et al. Erythropoietin in traumatic brain injury(EPO-TBI)：a double-blind randomised controlled trial[J]. Lancet，2015，386(10012)：2499-2506.
[19] ISHII T，ASAI T，OYAMA D，et al. Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin[J]. J Control Release，2012，160(1)：81-87., 百拇医药(吴雅云 庞鑫 刘刚)
[ 5 ] BANKS WA. From blood-brain barrier to blood-brain interface：new opportunities for CNS drug delivery[J]. Nat Rev Drug Discov，2016，15(4)：275-292.
[ 6 ] LI X，TSIBOUKLIS J，WENG T，et al. Nano carriers for drug transport across the blood-brain barrier[J]. J Drug Target，2017，25(1)：17-28.
, 百拇医药
[ 7 ] CHEN Z，ZHAI M，XIE X，et al. Apoferritin nanocage for brain targeted doxorubicin delivery[J]. Mol Pharm，2017，14(9)：3087-3097.
[ 8 ] AGULLA J，BREA D，CAMPOS F，et al. In vivo theranostics at the peri-infarct region in cerebral ischemia[J].Theranostics，2013，4(1)：90-105.
[ 9 ] GR?NBERG NV，JOHANSEN FF，KRISTIANSEN U，et al.Leukocyte infiltration in experimental stroke[J]. J Neuroinflammation，2013，10(1)：115.
, 百拇医药
[10] KIM JY，KAWABORI M，YENARI MA. Innate inflammatory responses in stroke：mechanisms and potential therapeutic targets[J]. Curr Med Chem，2014，21(18)：2076-2097.
[11] RODRIGO R，FERN?NDEZ-GAJARDO R，GUTI?RREZ R，et al. Oxidative stress and pathophysiology of ischemic stroke：novel therapeutic opportunities[J].CNS & Neurol Disord Drug Targets，2013，12(5)：698-714.
[12] HUANG J，UPADHYAY UM，TAMARGO RJ. Inflammation in stroke and focal cerebral ischemia[J].Surgical neurology，2006，66(3)：232-245.
, http://www.100md.com
[13] MOQIN AA. Disruption of ionic and cell volume homeostasis in cerebral ischemia： the perfect storm[J]. Pathophysiology，2007，14(3/4)：183-193.
[14] BOND? ML，DI GES? R，CRAPARO EF. Lipid nanoparticles for drug targeting to the brain[J]. Method Enzymol，2012，508：229-251.
[15] SONALI S，SINGH RP，SINGH N，et al. Transferrin liposomes of docetaxel for brain-targeted cancer applications：formulation and brain theranostics[J]. Drug Deliv，2016，23(4)：1261-1271.
, 百拇医药
[16] SHIMBO D，ABUMIYA T，SHICHINOHE H，et al.Post- ischemic intra-arterial infusion of liposome-encapsulated hemoglobin can reduce ischemia reperfusion injury[J]. Brain Res，2014，1554：59-66.
[17] ISHII T，ASAI T，OYAMA D，et al. Treatment of cerebral ischemia-reperfusion injury with PEGylated liposomes encapsulating FK506[J]. FASEB J，2013，27(4)：1362-1370.
[18] NICHOL A，FRENCH C，LITTLE L，et al. Erythropoietin in traumatic brain injury(EPO-TBI)：a double-blind randomised controlled trial[J]. Lancet，2015，386(10012)：2499-2506.
[19] ISHII T，ASAI T，OYAMA D，et al. Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin[J]. J Control Release，2012，160(1)：81-87., 百拇医药(吴雅云 庞鑫 刘刚)