SREBPs天然小分子抑制剂的药理学研究进展(6)
[33] ZHOU J，YOSHITOMI H，LIU T，et al. Isoquercitrin activates the AMP-activated protein kinase(AMPK)signal pathway in rat H4ⅡE cells[J]. BMC Complement Altern Med，2014，14：42.
[34] LIU H，ZHONG H，YIN Y，et al. Genistein has beneficial effects on hepatic steatosis in high fat-high sucrose diet-treated rats[J]. Biomed Pharmacother，2017，91：964- 969.
[35] GAUTAM J，KHEDGIKAR V，KUSHWAHA P，et al. Formononetin，an isoflavone，activates AMP-activated protein kinase/beta-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss[J]. Br J Nutr，2017，117(5)：645-661.
, http://www.100md.com
[36] QUAN HY，YUAN HD，JUNG MS，et al. Ginsenoside Re lowers blood glucose and lipid levels via activation of AMP-activated protein kinase in HepG2 cells and high-fat diet fed mice[J]. Int J Mol Med，2012，29(1)：73-80.
[37] MIN B，LEE H，SONG JH，et al. Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet[J]. Nutr Res Pract，2014，8(6)：655-661.
[38] DO MT，KIM HG，CHOI JH，et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling[J]. Food Chem，2013，136(2)：415-425.
, 百拇医药
[39] PATEL TP，SONI S，PARIKH P，et al. Swertiamarin：an active lead from enicostemma littorale regulates hepatic and adipose tissue gene expression by targeting PPAR-γ and improves insulin sensitivity in experimental NIDDM rat model[J]. Evid Based Complement Alternat Med，2013.DOI：10.1155/2013/358673.
[40] ZHANG J，TAN Y，YAO F，et al. Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c[J]. Mol Med Rep，2012，6(4)：815-820.
, 百拇医药
[41] HAO J，CHEN C，HUANG K，et al. Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the AKT signaling pathway[J]. Eur J Pharmacol，2014，745：152-165.
[42] DING L，LI J，SONG B，et al. Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway[J]. Toxicol Appl Pharmacol，2016，304：99-109.
[43] LEE JH，JUNG JY，JANG EJ，et al. Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1c pathway[J]. Exp Biol Med：Maywood，2015，240(4)：508-518.
[44] ZHANG Y，REN P，KANG Q，et al. Effect of tetramethylpyrazine on atherosclerosis and SCAP/SREBP-1c signaling pathway in ApoE-/- mice fed with a high-fat diet[J].Evid Based Complement Alternat Med，2017.DOI：10.1155/2017/3121989., 百拇医药(谢治深 赵振彪 张振强 王辉)
[34] LIU H，ZHONG H，YIN Y，et al. Genistein has beneficial effects on hepatic steatosis in high fat-high sucrose diet-treated rats[J]. Biomed Pharmacother，2017，91：964- 969.
[35] GAUTAM J，KHEDGIKAR V，KUSHWAHA P，et al. Formononetin，an isoflavone，activates AMP-activated protein kinase/beta-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss[J]. Br J Nutr，2017，117(5)：645-661.
, http://www.100md.com
[36] QUAN HY，YUAN HD，JUNG MS，et al. Ginsenoside Re lowers blood glucose and lipid levels via activation of AMP-activated protein kinase in HepG2 cells and high-fat diet fed mice[J]. Int J Mol Med，2012，29(1)：73-80.
[37] MIN B，LEE H，SONG JH，et al. Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet[J]. Nutr Res Pract，2014，8(6)：655-661.
[38] DO MT，KIM HG，CHOI JH，et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling[J]. Food Chem，2013，136(2)：415-425.
, 百拇医药
[39] PATEL TP，SONI S，PARIKH P，et al. Swertiamarin：an active lead from enicostemma littorale regulates hepatic and adipose tissue gene expression by targeting PPAR-γ and improves insulin sensitivity in experimental NIDDM rat model[J]. Evid Based Complement Alternat Med，2013.DOI：10.1155/2013/358673.
[40] ZHANG J，TAN Y，YAO F，et al. Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c[J]. Mol Med Rep，2012，6(4)：815-820.
, 百拇医药
[41] HAO J，CHEN C，HUANG K，et al. Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the AKT signaling pathway[J]. Eur J Pharmacol，2014，745：152-165.
[42] DING L，LI J，SONG B，et al. Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway[J]. Toxicol Appl Pharmacol，2016，304：99-109.
[43] LEE JH，JUNG JY，JANG EJ，et al. Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1c pathway[J]. Exp Biol Med：Maywood，2015，240(4)：508-518.
[44] ZHANG Y，REN P，KANG Q，et al. Effect of tetramethylpyrazine on atherosclerosis and SCAP/SREBP-1c signaling pathway in ApoE-/- mice fed with a high-fat diet[J].Evid Based Complement Alternat Med，2017.DOI：10.1155/2017/3121989., 百拇医药(谢治深 赵振彪 张振强 王辉)