炮制方法及提取溶剂对何首乌中主要成分含量的影响(4)
[ 7 ] 葛珍珍,张超,冯光远,等.何首乌提取物对正常与荷肝癌小鼠的急性肝毒性研究[J].中国药房,2014,25(15):1358-1361.
[ 8 ] 覃鲁珊,赵海平,赵艳玲,等.大黄蒽醌与鞣质对大鼠肝脏的保护和损伤双向作用[J].中国中西医结合杂志,2014,34(6):698-703.
[ 9 ] 马喆,赵珺睿,董冉冉,等.基于高内涵分析技术的何首乌提取物及其主要成分肝毒性研究[J].中草药,2016,47(22):4021-4029.
[10] LI HL,WANG XB,LIU Y,et al. Hepatoprotection and hepatotoxicity of Heshouwu,a Chinese medicinal herb:Context of the paradoxical effect[J]. Food Chem Toxicol,2017,108(Pt B):407-418.
, 百拇医药
[11] 吕旸,王伽伯,嵇扬,等.提取溶剂对何首乌肝细胞毒性的影响[J].中国实验方剂学杂志,2013,19(20):268-272.
[12] LIN LF,NI B,LIN HM,et al. Traditional usages,botany,phytochemistry,pharmacology and toxicology of Polygonum multiflorum Thunb.:A review[J]. J Ethnopharmacol,2015,159(15):158-183.
[13] LV GP,MENG LZ,HAN DQ,et al.,Effect of sample preparation on components and liver toxicity of Polygonum multiflorum[J]. J Pharm Biomed Anal,2015,109(10):105-111.
, 百拇医药
[14] 胡锡琴,李敏,杨红莲,等.何首乌中鞣质与二苯乙烯苷不同配比对大鼠肝功能指标的影[J].上海中医药杂志,2011,45(4):56-59.
[15] 胡錫琴,李娅琳,王磊.何首乌中鞣质对大鼠肝脏生化指标的影响[J].药物评价研究,2010,33(1):63-65.
[16] LP SP,TSE ASM,POON MKT,et al. Antioxidant activities of Polygonum multiflorum Thunb:in vivo and in vitro[J]. Phytother Res,1997,11(1):42-44.
[17] 翟旭峰,李柯,娄勇军,等.中药何首乌炮制前后特征化学成分的分析[J].中南药学,2016,14(7):704-708.
[18] 马致洁,李晓菲,吕旸,等.基于肝细胞毒价检测的何首乌炮制工艺比较研究[J].中国中药杂志,2015,40(12):2325-2329.
, 百拇医药
[19] ZHU ZW,LI J,GAO XM,et al. Simultaneous determination of stilbenes,phenolic acids,flavonoids and anthraquinones in Radix polygoni multiflori by LC-MS/MS[J]. J Pharm Biomed Anal,2012,62(2):162-166.
[20] LIANG ZT,CHEN HB,YU ZL,et al. Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry[J]. Chinese Medicine,2010,12(5):29-37.
[21] 卫生部药典委员会.中华人民共和国药典:一部[S]. 1963年版.北京:人民卫生出版社,1964:141-142.
[22] 卫生部药典委员会.中华人民共和国药典:一部[S]. 1977年版.北京:人民卫生出版社,1978:430-431.
[23] WU XQ,CHEN XZ,HUANG QC,et al. Toxicity of raw and processed roots of Polygonum multiflorum[J]. Fitoterapia,2012,83(3):469-475.
(收稿日期 :2017-08-29 修回日期:2017-11-08)
(编辑:刘 萍), 百拇医药(朱敏 姚毅 居文政 刘志辉 方祝元)
[ 8 ] 覃鲁珊,赵海平,赵艳玲,等.大黄蒽醌与鞣质对大鼠肝脏的保护和损伤双向作用[J].中国中西医结合杂志,2014,34(6):698-703.
[ 9 ] 马喆,赵珺睿,董冉冉,等.基于高内涵分析技术的何首乌提取物及其主要成分肝毒性研究[J].中草药,2016,47(22):4021-4029.
[10] LI HL,WANG XB,LIU Y,et al. Hepatoprotection and hepatotoxicity of Heshouwu,a Chinese medicinal herb:Context of the paradoxical effect[J]. Food Chem Toxicol,2017,108(Pt B):407-418.
, 百拇医药
[11] 吕旸,王伽伯,嵇扬,等.提取溶剂对何首乌肝细胞毒性的影响[J].中国实验方剂学杂志,2013,19(20):268-272.
[12] LIN LF,NI B,LIN HM,et al. Traditional usages,botany,phytochemistry,pharmacology and toxicology of Polygonum multiflorum Thunb.:A review[J]. J Ethnopharmacol,2015,159(15):158-183.
[13] LV GP,MENG LZ,HAN DQ,et al.,Effect of sample preparation on components and liver toxicity of Polygonum multiflorum[J]. J Pharm Biomed Anal,2015,109(10):105-111.
, 百拇医药
[14] 胡锡琴,李敏,杨红莲,等.何首乌中鞣质与二苯乙烯苷不同配比对大鼠肝功能指标的影[J].上海中医药杂志,2011,45(4):56-59.
[15] 胡錫琴,李娅琳,王磊.何首乌中鞣质对大鼠肝脏生化指标的影响[J].药物评价研究,2010,33(1):63-65.
[16] LP SP,TSE ASM,POON MKT,et al. Antioxidant activities of Polygonum multiflorum Thunb:in vivo and in vitro[J]. Phytother Res,1997,11(1):42-44.
[17] 翟旭峰,李柯,娄勇军,等.中药何首乌炮制前后特征化学成分的分析[J].中南药学,2016,14(7):704-708.
[18] 马致洁,李晓菲,吕旸,等.基于肝细胞毒价检测的何首乌炮制工艺比较研究[J].中国中药杂志,2015,40(12):2325-2329.
, 百拇医药
[19] ZHU ZW,LI J,GAO XM,et al. Simultaneous determination of stilbenes,phenolic acids,flavonoids and anthraquinones in Radix polygoni multiflori by LC-MS/MS[J]. J Pharm Biomed Anal,2012,62(2):162-166.
[20] LIANG ZT,CHEN HB,YU ZL,et al. Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry[J]. Chinese Medicine,2010,12(5):29-37.
[21] 卫生部药典委员会.中华人民共和国药典:一部[S]. 1963年版.北京:人民卫生出版社,1964:141-142.
[22] 卫生部药典委员会.中华人民共和国药典:一部[S]. 1977年版.北京:人民卫生出版社,1978:430-431.
[23] WU XQ,CHEN XZ,HUANG QC,et al. Toxicity of raw and processed roots of Polygonum multiflorum[J]. Fitoterapia,2012,83(3):469-475.
(收稿日期 :2017-08-29 修回日期:2017-11-08)
(编辑:刘 萍), 百拇医药(朱敏 姚毅 居文政 刘志辉 方祝元)