天然产物通过增加活性氧抗肿瘤的研究进展(6)
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[45] GUO P，WANG S，LIANG W，et al. Salvianolic acid B reverses multidrug resistance in HCT-8/VCR human colorectal cancer cells by increasing ROS levels[J]. Mol Med Rep，2017，15(2)：724-730.
[46] HAN X，HAN Y，ZHENG Y，et al. Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway，and exerts its anti-tumor activity in vivo[J]. PloS One，2017. DOI：10.1371/journal.pone.0175950.
(收稿日期：2018-07-17 修回日期：2019-01-04)
(編辑：张元媛), http://www.100md.com(孟路华 冯蕾 刘振)
[43] LIANG WZ，JAN CR，HSU SS. Cytotoxic effects of gastrodin extracted from the rhizome of Gastrodia elata Blume in glioblastoma cells，but not in normal astrocytes，via the induction of oxidative stress-associated apoptosis that involved cell cycle arrest and p53 activation[J]. Food Chem Toxicol，2017，107(Pt A)：280-292.
[44] XIANG Y，YE W，HUANG C，et al. Brusatol enhances the chemotherapy efficacy of gemcitabine in pancreatic cancer via the Nrf2 signalling pathway[J]. Oxid Med Cell Longev，2018. DOI：10.1155/2018/2360427.
[45] GUO P，WANG S，LIANG W，et al. Salvianolic acid B reverses multidrug resistance in HCT-8/VCR human colorectal cancer cells by increasing ROS levels[J]. Mol Med Rep，2017，15(2)：724-730.
[46] HAN X，HAN Y，ZHENG Y，et al. Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway，and exerts its anti-tumor activity in vivo[J]. PloS One，2017. DOI：10.1371/journal.pone.0175950.
(收稿日期：2018-07-17 修回日期：2019-01-04)
(編辑：张元媛), http://www.100md.com(孟路华 冯蕾 刘振)