香血藤中倍半萜类化学成分研究(5)
2. School of Pharmacy， Tianjin Medical University， Tianjin 300070， China)
[Abstract] Objective： To study the chemical constituents from Schisandra glaucescens. Method： The chemical constituents were separated and purifed with silica gel， gel column chromatography preparative HPLC， and their structures were identified by such spectral methods as MS and NMR. Result： Twelve compounds were separated from petroleum ether fractions， and identified as t-cadinol (1)， α-cadinol (2)， torreyol (3)， (+)-ent-epicubenol (4)， ent-T-muurolol (5)， (-)-15-hydroxycalamenene (6)， (-)-cubebol (7)， 4-epi-cubebol (8)， caryophyllenol-I (9)， caryophyllenol-II (10)， oxyphyllenodiols A (11)， caryolane-1，9β-diol (12). Conclusion： Compounds 4， 6-12 were separated from the genus for the first time， while compounds 1-12 were separated from this plant for the first time.
[Key words] Schisandra glaucescens； cadinane-type； cubebane-type； caryophyllane-type； caryolane-type； sesquiterpenes
doi：10.4268/cjcmm20122217
[责任编辑 孔晶晶], 百拇医药(张培培 高莎莎 张甜甜 陈家春 段宏泉 方进波)
[Abstract] Objective： To study the chemical constituents from Schisandra glaucescens. Method： The chemical constituents were separated and purifed with silica gel， gel column chromatography preparative HPLC， and their structures were identified by such spectral methods as MS and NMR. Result： Twelve compounds were separated from petroleum ether fractions， and identified as t-cadinol (1)， α-cadinol (2)， torreyol (3)， (+)-ent-epicubenol (4)， ent-T-muurolol (5)， (-)-15-hydroxycalamenene (6)， (-)-cubebol (7)， 4-epi-cubebol (8)， caryophyllenol-I (9)， caryophyllenol-II (10)， oxyphyllenodiols A (11)， caryolane-1，9β-diol (12). Conclusion： Compounds 4， 6-12 were separated from the genus for the first time， while compounds 1-12 were separated from this plant for the first time.
[Key words] Schisandra glaucescens； cadinane-type； cubebane-type； caryophyllane-type； caryolane-type； sesquiterpenes
doi：10.4268/cjcmm20122217
[责任编辑 孔晶晶], 百拇医药(张培培 高莎莎 张甜甜 陈家春 段宏泉 方进波)