市售不同厂家人参多糖注射液的质量评价(3)
[10]中国药典.一部[S].2010.
[11]张维杰.糖复合物生化研究技术[M].杭州：浙江大学出版社， 1999.
[12]李计萍.中药多糖有效部位研究中相对分子质量及分布研究相关问题探讨[J].药物分析杂志， 2009， 29(10)：1768.
[13]范慧红.2010年版《中国药典》中多糖类药物标准的修订[J]. 中国药学杂志， 2010， 45(17)：1294.
[14]张剑波， 田庚元.糖类的高效毛细管电泳[J].有机化学， 1998(18)：88.
[15]丁侃， 方积年.多糖类药物的毛细管电泳分析方法及其应用[J].色谱， 1999， 17(4)：346.
Quality evaluation of polysaccharide of
ginseng injections from different manufacturers
WAN Qin1，2， XIAO Wei1，2， WANG Zhen-zhong1，2 ， LIU Li-li1，2
(1.Jiangsu Kanion Pharmaceutical Co.， Ltd， Lianyungang 222001， China；
2.State Key Laboratory of Pharmaceutical Process New-tech for Chinese Medicine， Lianyungang 222001， China)
[Abstract]Objective： To evaluate injections of ginseng polysaccharide from 4 different manufacturers of 5 batches on the market.Method： Based on quality analysis， normal examinations were investigated， and monosaccharide composition and the molecular weight of polysaccharide in ginseng injections were performed.Result： Products from 4 different manufacturers were in line with the requirements of quality standard and Chinese Pharmacopeia (2010 edition).But there were great differences in molecular weight and monosaccharide composition.Conclusion： It is suggested to enhance the quality standard to ensure the medication safety use.
[Key words]polysaccharide of ginseng injection； quality evaluation； relative molecular weight； monosaccharide composition
doi：10.4268/cjcmm20130513
[责任编辑曹阳阳], http://www.100md.com(万琴 萧伟 王振中 刘莉莉)
[11]张维杰.糖复合物生化研究技术[M].杭州：浙江大学出版社， 1999.
[12]李计萍.中药多糖有效部位研究中相对分子质量及分布研究相关问题探讨[J].药物分析杂志， 2009， 29(10)：1768.
[13]范慧红.2010年版《中国药典》中多糖类药物标准的修订[J]. 中国药学杂志， 2010， 45(17)：1294.
[14]张剑波， 田庚元.糖类的高效毛细管电泳[J].有机化学， 1998(18)：88.
[15]丁侃， 方积年.多糖类药物的毛细管电泳分析方法及其应用[J].色谱， 1999， 17(4)：346.
Quality evaluation of polysaccharide of
ginseng injections from different manufacturers
WAN Qin1，2， XIAO Wei1，2， WANG Zhen-zhong1，2 ， LIU Li-li1，2
(1.Jiangsu Kanion Pharmaceutical Co.， Ltd， Lianyungang 222001， China；
2.State Key Laboratory of Pharmaceutical Process New-tech for Chinese Medicine， Lianyungang 222001， China)
[Abstract]Objective： To evaluate injections of ginseng polysaccharide from 4 different manufacturers of 5 batches on the market.Method： Based on quality analysis， normal examinations were investigated， and monosaccharide composition and the molecular weight of polysaccharide in ginseng injections were performed.Result： Products from 4 different manufacturers were in line with the requirements of quality standard and Chinese Pharmacopeia (2010 edition).But there were great differences in molecular weight and monosaccharide composition.Conclusion： It is suggested to enhance the quality standard to ensure the medication safety use.
[Key words]polysaccharide of ginseng injection； quality evaluation； relative molecular weight； monosaccharide composition
doi：10.4268/cjcmm20130513
[责任编辑曹阳阳], http://www.100md.com(万琴 萧伟 王振中 刘莉莉)