大洋纵列海鞘中的嘌呤和咔啉生物碱成分研究(3)
[11] Szantay C，Toth G，Marvanyos E，et al. A mainly 13C nuclear magnetic resonance investigation of some indolo[2，3，α] quinolizinylium salts[J]. J Chem Soc Perkin Trans II，1988，(4)：537.
[12] Qi S H，Zhang S，Yang L H，et al. Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis[J]. Nat Prod Res，2008，22：154.
[13] Kawate T，Nakagawa M，Yamazaki H，et al. Alkylation of 3，4，dihydro，β，carboline[J]. Chem Pharm Bull，1993，41(2)：287.
[14] Okuda T，Yoshida T，Shiota N，et al. L，3，carboxy，1，2，3，4，tetrahydro，β，carboline，a new amino acid from seeds of Aleurites fordii[J]. Phytochemistry，1975，14：2304.
[15] Zhai S H，Lu Y N，Fan，C Q，et al. Cerebroside and β，carboline alkaloids from the ascidian Ascidia longistriata[J]. Biochem Syst Ecol，2011，39：161.
Purine and carboline alkaloids from ascidian Symplegma oceania
ZHAO Shu，ming1， 2， LU Ya，nan1， TIAN Xiao，qing1， YANG Qiao1， YU Hui，juan1， FAN Cheng，qi
[Abstract] Five purine and carboline alkaloids were isolated from the methanol extract of the ascidian Symplegma oceania. Classic chromatographies including preparative HPLC were used for isolation and purification of the compounds. The structures were established as 6，methoxy，7，methyl，8，oxoguanine (1)， 2，methylimino，3，methyl，6，methylamino， 9H，purine (2)， 1，2，3，4，tetrahydro，β，carboline (3)， 1，2，3，4，tetrahydro，1，methyl，β，carboline (4) and 1，2，3，4，tetrahydro，β，carboline，3，carboxylic acid (5) by comparison the spectroscopic data (MS，1H， 13C，NMR) with those reported in the literatures. Compounds 2，5 were reported from the the genus Symplegma for the first time. The purine and carboline were the major alkaloid types of S. oceania.
[Key words] Styelidae； Symplegma oceania； purine； carboline
doi：10.4268/cjcmm20130718, http://www.100md.com(赵树明 陆亚男 田晓清 杨桥 于慧娟 樊成奇)
[12] Qi S H，Zhang S，Yang L H，et al. Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis[J]. Nat Prod Res，2008，22：154.
[13] Kawate T，Nakagawa M，Yamazaki H，et al. Alkylation of 3，4，dihydro，β，carboline[J]. Chem Pharm Bull，1993，41(2)：287.
[14] Okuda T，Yoshida T，Shiota N，et al. L，3，carboxy，1，2，3，4，tetrahydro，β，carboline，a new amino acid from seeds of Aleurites fordii[J]. Phytochemistry，1975，14：2304.
[15] Zhai S H，Lu Y N，Fan，C Q，et al. Cerebroside and β，carboline alkaloids from the ascidian Ascidia longistriata[J]. Biochem Syst Ecol，2011，39：161.
Purine and carboline alkaloids from ascidian Symplegma oceania
ZHAO Shu，ming1， 2， LU Ya，nan1， TIAN Xiao，qing1， YANG Qiao1， YU Hui，juan1， FAN Cheng，qi
[Abstract] Five purine and carboline alkaloids were isolated from the methanol extract of the ascidian Symplegma oceania. Classic chromatographies including preparative HPLC were used for isolation and purification of the compounds. The structures were established as 6，methoxy，7，methyl，8，oxoguanine (1)， 2，methylimino，3，methyl，6，methylamino， 9H，purine (2)， 1，2，3，4，tetrahydro，β，carboline (3)， 1，2，3，4，tetrahydro，1，methyl，β，carboline (4) and 1，2，3，4，tetrahydro，β，carboline，3，carboxylic acid (5) by comparison the spectroscopic data (MS，1H， 13C，NMR) with those reported in the literatures. Compounds 2，5 were reported from the the genus Symplegma for the first time. The purine and carboline were the major alkaloid types of S. oceania.
[Key words] Styelidae； Symplegma oceania； purine； carboline
doi：10.4268/cjcmm20130718, http://www.100md.com(赵树明 陆亚男 田晓清 杨桥 于慧娟 樊成奇)