新疆藁本化学成分的研究(6)
Chemical constituents of Conioselinum vaginatum
LI Xing，bo， QI Yao，dong， LIU Hai，tao*， ZHANG Jin， ZHANG Zhao， ZHANG Ben，gang
(Key Laboratory of Bioactive Substance and Resources Utilization of Chinese Herbal Medicine， Ministry of Education，Institute of Medicinal Plant Development， Chinese Academy of Medical Sciences，Peking Union Medical College， Beijing 100193， China)
[Abstract]Sixteen compounds were isolated from Conioselinum vaginatum by silica column chromatography over silica gel and Sephadex LH，20， as well as recrystallization. On the basis of their physical and chemical properties and spectral data， their structures were identified as ligustilide (1)， 1，3，dilinolein (2)， coniferaldehyde (3)， myristicin (4)， stigmasterol (5)， β-sitosterol (6)， vanillin (7)， pregnenolone (8)， bergapten (9)， xanthotoxin (10)， methyl indole，3，carboxylate (11)， ferulic acid (12)， (E)，3，methoxy，4，5，methylenedioxy，cinnamic alcohol (13)， p-hydroxybenzaldehyde (14)， 3，methoxy，4，5，methylenedioxy，acetophenone (15)， and α-(ethoxymethyl)，4，hydroxy， benzenemethanol (16). Among them， compound 15 was a new natural product， and compounds 2， 3， 10， 11， 14， and 16 were obtained from this genus for the first time.
[Key words]Conioselinum； Conioselinum vaginatum； chemical constituents
doi：10.4268/cjcmm20131018, 百拇医药(李兴博 齐耀东 刘海涛 张进 张昭 张本刚)
LI Xing，bo， QI Yao，dong， LIU Hai，tao*， ZHANG Jin， ZHANG Zhao， ZHANG Ben，gang
(Key Laboratory of Bioactive Substance and Resources Utilization of Chinese Herbal Medicine， Ministry of Education，Institute of Medicinal Plant Development， Chinese Academy of Medical Sciences，Peking Union Medical College， Beijing 100193， China)
[Abstract]Sixteen compounds were isolated from Conioselinum vaginatum by silica column chromatography over silica gel and Sephadex LH，20， as well as recrystallization. On the basis of their physical and chemical properties and spectral data， their structures were identified as ligustilide (1)， 1，3，dilinolein (2)， coniferaldehyde (3)， myristicin (4)， stigmasterol (5)， β-sitosterol (6)， vanillin (7)， pregnenolone (8)， bergapten (9)， xanthotoxin (10)， methyl indole，3，carboxylate (11)， ferulic acid (12)， (E)，3，methoxy，4，5，methylenedioxy，cinnamic alcohol (13)， p-hydroxybenzaldehyde (14)， 3，methoxy，4，5，methylenedioxy，acetophenone (15)， and α-(ethoxymethyl)，4，hydroxy， benzenemethanol (16). Among them， compound 15 was a new natural product， and compounds 2， 3， 10， 11， 14， and 16 were obtained from this genus for the first time.
[Key words]Conioselinum； Conioselinum vaginatum； chemical constituents
doi：10.4268/cjcmm20131018, 百拇医药(李兴博 齐耀东 刘海涛 张进 张昭 张本刚)