改善中药口服生物利用度的剂型设计的研究(6)
2. Key Laboratory of New Drug Delivery System of Chinese Meteria Medica，Jiangsu Provincial Academy of Chinese Medicine， Nanjing 210028， China) [Abstract] Both chemical drugs and traditional Chinese medicines have the problem of low bioavailability. However， as traditional Chinese medicines are a multi-component complex， their dosage forms are required to be designed in line with their characteristics， in order to improve the bioavailability of traditional Chinese medicines. Traditional Chinese medicines are mostly prepared into pill， powder， paste， elixir and decoction， but with such drawbacks as high administration dose and poor efficacy. With the process of modernization of traditional Chinese medicines， new-type preparations have be developed and made outstanding achievements. However， they fail to make an organic integration between traditional Chinese medicine theories and modern preparation theories. Characteristics of traditional Chinese medicines are required to be taken into account during the development of traditional Chinese medicines. In the article， multi-component preparation technology was adopted to establish a multi-component drug release system of traditional Chinese medicines on the basis of multiple components of traditional Chinese medicines.
[Key words] multi-component traditional Chinese medicine； preparation technology； bioavailability； multi-component drug delivery system of traditional Chinese medicines
doi：10.4268/cjcmm20131734
[责任编辑 曹阳阳], http://www.100md.com(夏海建 张振海 姚冬冬 贾晓斌)
[Key words] multi-component traditional Chinese medicine； preparation technology； bioavailability； multi-component drug delivery system of traditional Chinese medicines
doi：10.4268/cjcmm20131734
[责任编辑 曹阳阳], http://www.100md.com(夏海建 张振海 姚冬冬 贾晓斌)