计算机辅助药物设计在天然产物多靶点药物研发中的应用(5)
[27] Dong G， Wang S， Miao Z， et al. New tricks for an old natural product： discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations[J]. J Med Chem， 2012， 55(17)： 7593.[28] Keller T H， Pichota A， Yin Z. A practical view of ′druggability′[J]. Curr Opin Chem Biol ......
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