中药对骨髓间充质干细胞增殖、凋亡及分化的影响研究进展(5)
Kunming Medical University， Kunming 650500， China)
[Abstract] Bone marrow mesenchymal stem cells (BMSCs) are a kind of pluripotent stem cells derived from bone marrows， which can not only support hematopoiesis， but also have capabilities of multidifferentiation， high-proliferation and self-renewing. They have become one of hotspots in stem cell studies. Studies on in vitro intervention with BMSCs with TCMs have made remarkable progress in recent years. According to the findings， some traditional Chinese medicines can promote proliferation of BMSCs， some can inhibit the apoptosis of BMSCs， while others can induce BMSCs to differentiate into multiple cell types， such as osteoblast. Furthermore， some studies also involved relevant action mechanisms. The authors summarized the advance in relevant studies by reference to relevant literatures of this field.
[Key words] traditional Chinese medicine； bone marrow mesenchymal stem cells； proliferation； apoptosis； differentiation； advance in studies
doi：10.4268/cjcmm20141509
[责任编辑 张宁宁], http://www.100md.com(方健康 周轶平 李玛琳)
[Abstract] Bone marrow mesenchymal stem cells (BMSCs) are a kind of pluripotent stem cells derived from bone marrows， which can not only support hematopoiesis， but also have capabilities of multidifferentiation， high-proliferation and self-renewing. They have become one of hotspots in stem cell studies. Studies on in vitro intervention with BMSCs with TCMs have made remarkable progress in recent years. According to the findings， some traditional Chinese medicines can promote proliferation of BMSCs， some can inhibit the apoptosis of BMSCs， while others can induce BMSCs to differentiate into multiple cell types， such as osteoblast. Furthermore， some studies also involved relevant action mechanisms. The authors summarized the advance in relevant studies by reference to relevant literatures of this field.
[Key words] traditional Chinese medicine； bone marrow mesenchymal stem cells； proliferation； apoptosis； differentiation； advance in studies
doi：10.4268/cjcmm20141509
[责任编辑 张宁宁], http://www.100md.com(方健康 周轶平 李玛琳)