海洋Penicillium sp. FJ—1中一个抗真菌活性的新橙酮苷(4)
A summary of MIC and MFC values of compound 1 was shown in Table 2. Compound 1 exhibited potent antifungal activity against Candida sp. Production of extracellular phospholipase is a well-known virulence factor in Candida to degrade cell membrane of host tissue. Compound 1 increased the Pz values of Candida krusei in a dose-dependent manner(10%-25%)(Table 3) ......
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