葛根素对PI3K/AKT通路介导PASMCS凋亡的影响(5)
为了研究Pue通过PI3K/AKT而发挥作用,本实验还检测了Pue和LY294002单独及协同对p-AKT表达的影响,结果显示Pue与LY294002可协同抑制AKT磷酸化。这表明Pue可能通过调控PI3K/AKT通路来诱导PASMCs凋亡。
[参考文献]
[1] Ghofrani H A, Voswinckel R, Reichenberger F, et al. Hypoxia and non-hypoxia-related pulmonary hypertention established and new therapies[J]. Cardiovasc Res ......
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[参考文献]
[1] Ghofrani H A, Voswinckel R, Reichenberger F, et al. Hypoxia and non-hypoxia-related pulmonary hypertention established and new therapies[J]. Cardiovasc Res ......
您现在查看是摘要页,全文长 2165 字符。