脾气虚证大鼠尿液生物标记物的识别及其生物学意义(5)
[12] Li Y, Wang L, Ju L, et al. A systematic strategy for screening and application of specific biomarkers in hepatotoxicity using metabolomics combined with ROC curves and SVMs[J]. Toxicol Sci,2016,150(2):390.
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[18] Westerhuis J A,Fursy R,Bret L,et al. Indole can act as an extracellular signal to regulate biofilm formation of Escherichia coli and other indole-producing bacteria[J]. Can J Microbiol,2003,49(7):443.
[19] 張伟戈,廖玉婷,孟捷. 肠黏膜通透性增高与IBD、IBS发病机制和脾气虚关系探讨[J]. 辽宁中医药大学学报,2017(1):187.
[20] 成映霞,杜娟,杨晓轶,等. 脾气虚大鼠小肠组织Ca2+/CaM信号通路关键分子的表达变化[J]. 中华中医药杂志,2015(10):3624.
[21] 姜洪华,周福生,廖荣鑫,等. 不同病种的脾气虚证患者吸收细胞线粒体超微结构的观察[J]. 广东医学,2008,29(4):548.
[22] 周昕欣,王彩霞. 补中益气汤治疗脾气虚证大鼠肌无力的机制研究[J]. 中国实验方剂学杂志,2015,21(3):92.
[23] 贾连群,甄毕贤,徐荧,等. 应用液质联用技术研究脾虚大鼠血清代谢物谱群特征[J]. 中国中西医结合杂志,2016,36(3):359.
[责任编辑 张燕], 百拇医药(刘武平 李婵艺 黄晶 廖婧竹 马文杰 陈宏远 芮雯)
[13] Rinaudo P,Thévenot E A. Biosigner:a new method for signature discovery from omics data[EB/OL].[2017-06-14]. https://bioconductor.org/packages/release/bioc/vignettes/biosigner/inst/doc/biosigner-vignette.pdf.
[14] Luan H,Liu L F, Tang Z,et al. Comprehensive urinary metabolomic profiling and identification of potential noninvasive marker for idiopathic Parkinson′s disease[J]. Sci Rep,2015,5(1):13888.
[15] Liang X,Chen X,Liang Q,et al. Metabonomic study of Chinese medicine Shuanglong formula as an effective treatment for myocardial infarction in rats[J]. J Proteome Res,2011,10(2):790.
[16] Westerhuis J A,Hoefsloot H C J,Smit S,et al. Assessment of PLSDA cross validation[J]. Metabolomics,2008,4(1):81.
[17] Schrcksnadel K,Wirleitner B,Winkler C,et al. Monitoring tryptophan metabolism in chronic immune activation[J]. Clin Chim Acta,2006,364(1):82.
[18] Westerhuis J A,Fursy R,Bret L,et al. Indole can act as an extracellular signal to regulate biofilm formation of Escherichia coli and other indole-producing bacteria[J]. Can J Microbiol,2003,49(7):443.
[19] 張伟戈,廖玉婷,孟捷. 肠黏膜通透性增高与IBD、IBS发病机制和脾气虚关系探讨[J]. 辽宁中医药大学学报,2017(1):187.
[20] 成映霞,杜娟,杨晓轶,等. 脾气虚大鼠小肠组织Ca2+/CaM信号通路关键分子的表达变化[J]. 中华中医药杂志,2015(10):3624.
[21] 姜洪华,周福生,廖荣鑫,等. 不同病种的脾气虚证患者吸收细胞线粒体超微结构的观察[J]. 广东医学,2008,29(4):548.
[22] 周昕欣,王彩霞. 补中益气汤治疗脾气虚证大鼠肌无力的机制研究[J]. 中国实验方剂学杂志,2015,21(3):92.
[23] 贾连群,甄毕贤,徐荧,等. 应用液质联用技术研究脾虚大鼠血清代谢物谱群特征[J]. 中国中西医结合杂志,2016,36(3):359.
[责任编辑 张燕], 百拇医药(刘武平 李婵艺 黄晶 廖婧竹 马文杰 陈宏远 芮雯)