脐带血中葡萄糖—6—磷酸脱氢酶检测对新生儿高胆红素血症的诊断价值(1)
摘要:目的:探讨检测脐带血中葡萄糖-6-磷酸脱氢酶(G6PD)活性对诊断新生儿高胆红素血症的临床意义。方法:采用紫外速率定量法,对高胆红素血症组174例新生儿G6PD活性进行定量测定,并与非高胆红素血症组166例新生儿进行比较。结果:高胆红素血症组新生儿G6PD阳性率为12.07%,非高胆红素血症组新生儿G6PD阳性率为0%,两组G6PD阳性率差异显著,具有统计学意义(P<0.05);高胆红素血症组新生儿G6PD活性显著低于非高胆红素血症组,差异亦具有统计学意义(P<0.05);高胆红素组新生儿血清总胆红素水平与G6PD活性呈负性显著相关(P<0.05)。结论:G6PD活性可作为诊断新生儿高胆红素血症的重要指标,对G6PD缺乏的高胆红素血症新生儿进行及时干预,可有效控制G6PD缺乏引起的新生儿溶血及核黄疸病情。
关键词:高胆红素血症;葡萄糖-6-磷酸脱氢酶;新生儿
Diagnostic value of glucose-6-phosphate dehydrogenase in umbilical cord blood for neonates with hyperbilirubinemi
ZENG Chun-xia
ABSTRACT Objective:To explore the clinical significance of detecting the activity of glucose-6-phosphate dehydrogenase (G6PD) in neonates with hyperbilirubinemi. Methods: The activity of G6PD was detected in 174 neonates with hyperbilirubinemi ......
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关键词:高胆红素血症;葡萄糖-6-磷酸脱氢酶;新生儿
Diagnostic value of glucose-6-phosphate dehydrogenase in umbilical cord blood for neonates with hyperbilirubinemi
ZENG Chun-xia
ABSTRACT Objective:To explore the clinical significance of detecting the activity of glucose-6-phosphate dehydrogenase (G6PD) in neonates with hyperbilirubinemi. Methods: The activity of G6PD was detected in 174 neonates with hyperbilirubinemi ......
您现在查看是摘要页,全文长 3644 字符。