氨基糖苷类在临床中应注意的问题(1)
摘要:氨基糖苷类抗生素(aminoglycosides)是由链霉菌或小单孢菌培养液中提取或以天然品为原料半合成制取而得的一类水溶性较强的碱性抗生素。主要包括:链霉素、新霉素、庆大霉素、卡那毒素、妥布霉素以及阿米卡星、奈替米星等。 氨基糖苷类抗生素对革兰阴性杆菌作用范围大,强而持久,且还具有较长的抗菌后效作用(Post Antibiotic Effect PAE)。从抗菌作用的特点看,氨基糖苷类是一类较优良的抗生素,然而,该类药物的治疗浓度范围窄,不良反应较常见,其中有些是不可逆毒性,这是限制它在临床广泛使用的主要原因。
关键词:氨基糖苷类;临床用药
Aminoglycoside in clinical problems should be paid attention to
Xu ShengTian ZongpingHu Xing
Abstract:Aminoglycoside antibiotics (aminoglycosides) culture by Streptomyces or small single spore bacterium or extracted with natural products as a raw material of preparing semisynthetic and type of water soluble strong alkaline antibiotics. Mainly includes: streptomycin ......
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关键词:氨基糖苷类;临床用药
Aminoglycoside in clinical problems should be paid attention to
Xu ShengTian ZongpingHu Xing
Abstract:Aminoglycoside antibiotics (aminoglycosides) culture by Streptomyces or small single spore bacterium or extracted with natural products as a raw material of preparing semisynthetic and type of water soluble strong alkaline antibiotics. Mainly includes: streptomycin ......
您现在查看是摘要页,全文长 3694 字符。