白三烯受体拮抗剂对呼吸道合胞病毒感染后气道炎症的作用探讨(1)
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【基金项目】东莞市科技计划医疗卫生类科研项目(编号:2010125152274)。东莞市医疗卫生单位科技项目经费资助。
【摘要】目的: 探究白三烯受体拮抗剂对呼吸道合胞病毒感染后气道炎症效应。探究方法:选择156例轻中度RSV毛细支气管炎患儿作为研究对象,症状控制后随机分三组,利用ELISA法检测各组患者血清中ECP、 LTE4的浓度,并随访一年。结果: 156例RSV毛细支气管炎患儿ECP、LTE4水平在急性期、恢复期均较健康对照组明显升高。顺尔宁干预组及激素干预组患儿干预结束后ECP、LTE4水平下降。结论:白三烯受体拮抗剂能够减少LTE4的释放减少喘息发作,对毛细支气
【关键词】白三烯受体拮抗剂;嗜酸性粒细胞阳离子蛋白;白三烯
【中图分类号】R725.6【文献标识码】A【文章编号】1044-5511(2011)11-0021-02
【Abstract】Objective: To explore the effect of leukotriene receptor antagonist on respiratory syncytial virus infection after airway inflammation effect. Research methods: 156 cases of mild and moderate RSV patients with bronchiolitis as a research object, symptoms after controlling were randomly divided into three groups, using the method of ELISA were detected in sera of patients with ECP, LTE4 concentrations, and followed up for one year ......
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