【摘要】临床用于支气管哮喘诊断与治疗监测主要是根据临床症状、肺功能检测、支气管激发试验等，它们不能直接反应气道炎症；诱导痰分析虽能直接反应气道炎症，但较难在临床得到广泛应用。目前很多研究发现呼出气一氧化氮与气道炎症、气道高反应性具有显著相关性，临床研究发现呼出气一氧化氮对于支气管哮喘诊断与治疗具有重要意义；而且呼出气一氧化氮检测简便、快捷、安全。

    【关键词】呼出气一氧化氮;哮喘;气道炎症

    【中图分类号】R571.3【文献标识码】A【文章编号】1004-5511(2012)06-0324-02

    【Abstract】Clinical diagnosis and treatment for bronchial asthma monitoring is primarily based on clinical symptoms, pulmonary function tests, bronchial provocation test. They can not directly response to airway inflammation; analysis of induced sputum can direct response to airway inflammation, but is difficult to used extensively in clinic. At present, many studies have found that exhaled nitric oxide and airway inflammation, airway hyperresponsiveness have significant correlation, And exhaled nitric oxide assay is simple, quick, safe.

    【Key words】Exhaled nitric oxide；Asthma；Airway inflammation

    1呼出气一氧化氮的来源

    呼出气一氧化氮是由多种细胞分泌产生 ......