【中图分类号】R735.7 【文献标识码】A

    Construction and validation of a prognostic prediction model for osteosarcoma inchildrenbasedontheSEERdatabase

    ZHANG Lei1，LI Yuwan2，WU Yindan2，XU Zhi4，SHAO Jinfu5

    1. Department of Pediatrics， Zhangjiagang Fifth People's Hospital， Zhangjiagang 2156oo， Jiangsu Province， China

    2.DepartmentofOrthopedics，TheFirstAfiliatedHospital，ZhejiangUniversitySchoolofMedicine， Hangzhou 310009， China

    3.Department of Pediatric Surgery， Zhangjiagang First People's Hospital， Zhangjiagang 2156oo，JiangsuProvince，China

    4.DepartmentofOrthopedics，ZhangjiagangFifthPeople'sHospital，Zhangjiagang2156oo，JiangsuProvince，China 5.Departmentofediatricedicin，ZhangjagangFstPeople'sHospital，Zhangjagang2156oo，JiangsuProvince，China Corresponding author： SHAO Jinfu，Email： sjf502@163.com

    【Abstract】 Objective To construct and validate a nomogram model for predicting the survival prognosis of pediatric osteosarcoma patients. Methods Data were collcted from pediatric patients diagnosed with osteosarcoma based on the U.S.SEER databasebetween 20o0 and 2021，aged lessthan 14 years.Patients were randomly divided into a training set and a validation set in a 7：3 ratio.Univariate and multivariate Cox proportional hazards models were used to identify factors afecting survival ......