【中图分类号】 R697+.3 ； R737.25 【文献标识码】A

    The role of zinc homeostasis in prostate diseases and potential mechanisms

    HAN Yutong122， FAN Jiuming1.2， WANG Tiankun1：2， QI Zihao122， ZHANG Yuanyuan2， HOU Junqing34

    1. School of Clinical Medicine，Henan University，Kaifeng 4754oo，HenanProvince， China

    2.Center for Evidence-Based and Translational Medicine，Zhongnan Hospitalof Wuhan University，Wuhan 430071， China

    3.DepartmentofUrology，Kaifeng155Hospital，ChinaRongTongMedicalHealthcareGroupCo.Ltd，Kaifeng47540o，Henan Province， China

    4.Henan Engineering Research Center of Prostate Disease Preventionand Diagnosis， Kaifeng475400，Henan Province，China

    Corresponding authors： HOU Junqing， Email： hjq0418@sina.com; ZHANG Yuanyuan， Email： zhangyy_ph@163.com

    【Abstract】 Zinc is an essential trace element in the human body， participating in various critical physiological functions and being highly concentrated in the prostate gland. Studies have shown that prostate diseases might be associated with zinc imbalance.Investigating the regulatory mechanisms and dynamic patterns of zinc homeostasis in prostate diseases holds significant importance for exploring the pathogenesis ......