MMF治疗IgA肾病临床研究进展(1)
[摘要]IgA肾病是世界性的疾病,也是最常见的原发性肾小球肾炎。多达15-20%的患者在有明显症状的10年内和30-40%的患者在诊断后的20年内发展至终末期肾病。MMF是一种抗代谢免疫抑制剂,逐渐被用于治疗IgA肾病。本文就MMF治疗IgA肾病的疗效和安全性作一综述。关键词:MMFIgA肾病尿蛋白
Abstract: Immunoglobulin A (IgA) nephropathy is a worldwide disease, and is the most commom type of glomerulonephritis, that causes end-stage kidney disease (ESRD) in up to 15-20% of affected patients within 10 years from the apparent onset of disease and in up to 30-40% of individuals within 20 years from diagnosis. Mycophenolate mofetil (MMF) is an antimetabolic immunosuppressant ......
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