【摘 要】目的：观察卵白蛋白口服液对小鼠免疫功能的影响。方法：BALB/c小鼠连续灌胃30天后检测碳廓清能力、迟发型变态反应、抗体生成细胞数、血清溶血素水平、巨噬细胞吞噬鸡红细胞能力、NK细胞活性及ConA诱导的脾淋巴细胞转化能力等免疫指标。结果：卵白蛋白口服液对小鼠的脏/体比值、碳廓清能力及NK细胞活性无明显影响；对迟发型变态反应、抗体生成细胞数、HC 50、巨噬细胞吞噬鸡红细胞能力及ConA诱导的小鼠淋巴细胞转化有显著作用。结论：卵白蛋白口服液能增强小鼠免疫功能。

    【关键词】卵白蛋白；免疫功能；小鼠

    【中图分类号】R 285 【文献标识码】A 【文章编号】1004- 7484(2012)04- 0123- 02

    【Abstract】Objective：To observe the impact of the ovalbumin oral liquid on immune function in mice. Methods： Given BALB/c mice the ovalbumin oral liquid intragastrically 30 days, we detected immune indicators, including carbon clearance ability, delayed type hypersensitivity, antibody-producing cell count, serum hemolysin level, macrophage phagocytosis of chicken erythrocytes capacity, NK cell activity and ConA-induced lymphocyte transformationability, etc. Results：The ovalbumin oral liquid had no obvious influence on organ weight / body weight , carbon clearance and NK cell activity in mice. However, it had significant effect on delayed type hypersensitivity, antibody-producing cell count, HC50, macrophage phagocytosis of chicken erythrocytes capacity and ConA-induced lymphocyte transformationability. Conclusion：The ovalbumin oral liquid could enhance immune function in mice. ......