【摘 要】目的：探讨聚乙二醇干扰素α-2a联合利巴韦林治疗慢性丙型病毒性肝炎的临床效果。方法：选取我院2007年5月～2013年1月收治的100例慢性丙型肝炎患者，抽签随机分为治疗组与对照组各50例，治疗组予以聚乙二醇干扰素α-2a联合利巴韦林治疗，对照组予以干扰素α-2a皮下注射联合利巴韦林治疗，对比2组疗效。结果：两组各阶段ALT复常率、应答率对比无统计学差异(P>0.05)。治疗组不良发应例数均少于对照组(P<0.05)。结论：聚乙二醇干扰素α-2a联合利巴韦林治疗慢性丙型病毒性肝炎与干扰素α-2a皮下注射联合利巴韦林疗法应答率等方面相似，不良反应发生率略低。

    【关键词】聚乙二醇干扰素；利巴韦林；慢性病型病毒性肝炎；治疗效果

    【中图分类号】R512.63 【文献标识码】a 【文章编号】1004-7484(2014)04-1888-01

    Clinical observation of peginterferon α-2a and ribavirin treatment of chronic hepatitis C

    Quanshunai

    (The people's Hospital of Jilin province Tumen City Department of infectious diseases 133100)

    【Abstract】Objective： To investigate peginterferon α-2a and ribavirin treatment of chronic hepatitis C clinical results. Methods： 100 cases of hepatitis in patients with chronic hepatitis C in our hospital during May 2007 - January 2013 were randomly divided into the treatment group and control group(50 cases in each group) ......