军团菌毒力因子致病作用的研究进展(2)
[3]Hoffman PS, Ripley M, Weeratna R. Cloning and nucleotide sequence of a gene (ompS) encoding the major outer membrane protein of Legionella pneumophila\ J Bacteriol, 1992, 174(3):914-920.
[4]Bellinger-Kawahara C, Horwitz MA. Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes\. J Exp Med, 1990, 172(4):1201-1210.
, http://www.100md.com
[5]Fischer G, Bang H, Ludwig B, et al. Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity\. Mol Microbiol, 1992, 6(10):1375-1383.
[6]Helbig JH, Knig B, Knospe H, et al. The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells\. Biol Chem, 2003, 384(1):125-137.
[7]Garduo RA, Garduo E, Hoffman PS. Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model\. Infect Immun, 1998, 66(10):4602-4610.
, 百拇医药
[8]Swanson MS, Hammer BK. Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages\. Annu Rev Microbiol, 2000, 54:567-613.
[9]Stone BJ, Abu Kwaik Y. Expression of multiple pili by Legionella pneumophila: identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells\. Infect Immun, 1998, 66(4):1768-1775.
[10]Heuner K, Steinert M. The flagellum of Legionella pneumophila and its link to the
, http://www.100md.com
expression of the virulent phenotype\. Int J Med Microbiol, 2003, 293:133-143.
[11]Gerlach R G,Hensel M. Protein secretion systems and adhesions: the molecular armory of Gram-negative pathogens\. Int J Med Microbiol,2007, 297:401-415.
[12]Ridenour DA, Cirillo SL, Feng S, et al. Identification of a gene that affects the efficiency of host cell infection by Legionella pneumophila in a temperature-dependent fashion\. Infect
, 百拇医药
Immun, 2003, 71(11):6256-6263.
[13]Samrakandi MM, Cirillo SL, Ridenour DA, et al. Genetic and phenotypic between Legionella pneumophila strains\. J Clin Microbiol, 2002, 40:1352-1362.
[14]Molmeret M, Santic M, Asare R, et al. Rapid escape of the dot/icm mutants of Legionella
pneumophila into the cytosol of mammalian and protozoan cells\. Infect Immun,2007,75(7):3290-3304.
, http://www.100md.com
[15]Rossier O, Starkenburg SR, Cianciotto NP. Legionella pneumophila type Ⅱ protein secretion promotes virulence in the A/J mouse model of Legionnaires'disease pneumonia\. Infect Immun,2004, 72(1):310-321.
[16]Viswanathan VK, Edelstein PH, Pope CD, et al. The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence\. Infect Immun,2000, 68(3):1069-1079.
[17]Viswanathan VK, Kurtz S, Pedersen LL, et al. The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element\. Infect Immun, 2002, 70(4):1842-1852.
, http://www.100md.com
[18]Edelstein PH, Hu BF, Higa F,et al. Ivg A, a novel legionella pneumophila virulence factor\.
Infect Immun, 2003, 71(5):2394-2403.
[19]Zusman T, Gal-Mor O, Segal G, et al. Characterization of a Legionella pneumophila relA insertion mutant and toles of RelA and RpoS in virulence gene expression\. J Bacteriol, 2002, 184(1):67-75.
(收稿日期:2009-04-20), http://www.100md.com(朱 俊 盛跃颖 陈 敏)
[4]Bellinger-Kawahara C, Horwitz MA. Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes\. J Exp Med, 1990, 172(4):1201-1210.
, http://www.100md.com
[5]Fischer G, Bang H, Ludwig B, et al. Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity\. Mol Microbiol, 1992, 6(10):1375-1383.
[6]Helbig JH, Knig B, Knospe H, et al. The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells\. Biol Chem, 2003, 384(1):125-137.
[7]Garduo RA, Garduo E, Hoffman PS. Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model\. Infect Immun, 1998, 66(10):4602-4610.
, 百拇医药
[8]Swanson MS, Hammer BK. Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages\. Annu Rev Microbiol, 2000, 54:567-613.
[9]Stone BJ, Abu Kwaik Y. Expression of multiple pili by Legionella pneumophila: identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells\. Infect Immun, 1998, 66(4):1768-1775.
[10]Heuner K, Steinert M. The flagellum of Legionella pneumophila and its link to the
, http://www.100md.com
expression of the virulent phenotype\. Int J Med Microbiol, 2003, 293:133-143.
[11]Gerlach R G,Hensel M. Protein secretion systems and adhesions: the molecular armory of Gram-negative pathogens\. Int J Med Microbiol,2007, 297:401-415.
[12]Ridenour DA, Cirillo SL, Feng S, et al. Identification of a gene that affects the efficiency of host cell infection by Legionella pneumophila in a temperature-dependent fashion\. Infect
, 百拇医药
Immun, 2003, 71(11):6256-6263.
[13]Samrakandi MM, Cirillo SL, Ridenour DA, et al. Genetic and phenotypic between Legionella pneumophila strains\. J Clin Microbiol, 2002, 40:1352-1362.
[14]Molmeret M, Santic M, Asare R, et al. Rapid escape of the dot/icm mutants of Legionella
pneumophila into the cytosol of mammalian and protozoan cells\. Infect Immun,2007,75(7):3290-3304.
, http://www.100md.com
[15]Rossier O, Starkenburg SR, Cianciotto NP. Legionella pneumophila type Ⅱ protein secretion promotes virulence in the A/J mouse model of Legionnaires'disease pneumonia\. Infect Immun,2004, 72(1):310-321.
[16]Viswanathan VK, Edelstein PH, Pope CD, et al. The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence\. Infect Immun,2000, 68(3):1069-1079.
[17]Viswanathan VK, Kurtz S, Pedersen LL, et al. The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element\. Infect Immun, 2002, 70(4):1842-1852.
, http://www.100md.com
[18]Edelstein PH, Hu BF, Higa F,et al. Ivg A, a novel legionella pneumophila virulence factor\.
Infect Immun, 2003, 71(5):2394-2403.
[19]Zusman T, Gal-Mor O, Segal G, et al. Characterization of a Legionella pneumophila relA insertion mutant and toles of RelA and RpoS in virulence gene expression\. J Bacteriol, 2002, 184(1):67-75.
(收稿日期:2009-04-20), http://www.100md.com(朱 俊 盛跃颖 陈 敏)