首发与复发抑郁症患者持续性操作测验分析(1)
【摘要】目的:分析首发与复发抑郁症患者持续性操作测验结果。方法:选择我院2016年7月至2017年8月期间收治的住院抑郁症患者68例,依据首发和复发将其分为两组,即A组(n=34)和B组(n=34),之后选取同期入院的健康人群34例,将其设为C组,A组和B组患者均接受抗抑郁治疗,之后利用HAMD量表和持续性操作试验对所有受检人员进行检测,最后总结所得结果。结果:比对A组和B组患者治疗后的HAMD评分,前者改善优于后者,组间数据结果证实后差异呈P<005,统计学意义存在。另外,A组患者的持续操作试验结果与C组差异呈P>005,B组患者的持续操作试验结果与C组差异P<005,统计学意义存在。结论:复发抑郁症患者损害较为严重,同时具有较长的恢复用时,首发抑郁症患者坚持治疗和积极预防至关重要。
【关键词】首发与复发抑郁症;持续性操作测验;结果分析
【中圖分类号】R749.4+1
【文献标志码】B
, 百拇医药
【文章编号】1005-0019(2018)07-020-01
Abstract Objective:To analyze the results of continuous operation test for patients with primary and recurrent depression.Methods: 68 patients with inpatient depression who were admitted to our hospital between July 2016 and August 2017 were divided into two groups, namely, group A(N = 34) and group B(N = 34), according to the starting point and recurrence. Then 34 healthy people were admitted to the hospital in the same period. It was set to group C, group A and group B patients received antidepressant treatment, and then all the subjects were tested using the HAMD scale and continuous operation tests, and the results were summarized.Results: Compared with HAMD scores in group A and B patients, the former improved better than the latter, and the data between groups confirmed that the difference was P 005, which was statistically significant. In addition, the results of the continuous operation test in group A patients and the C group were P > 005, and the results of the continuous operation test in group B patients and the C group were P 005, which was statistically significant. Conclusion: The patients with recurrent depression suffered more serious damage and had longer recovery.
, 百拇医药
在精神科疾病中抑郁症较为常见,其不仅会发生情感症状,同时会损害认知功能,即使治愈后也难以将认知功能恢复至最佳状态。据有关资料显示,抑郁症认知功能会受到诸多因素的影响,如:病情和发作次数,就复发抑郁症患者而言,其认知损害更为显著,同时会增加恢复难度[1]。为此,此研究选择我院近一年(2016年7月至2017年8月)收治的住院抑郁症患者68例,对其实施持续性操作测验得到价值进行探究。
1对象与方法
11基础信息此次研究抽取的住院抑郁症患者68例,收治时间为2016年7月至2017年8月。将所有患者依据首发和复发均分A组(n=34)和B组(n=34),之后选取同期入院的健康人群34例,将其设为C组。A组患者中,男性患者、女性患者分别为22例、12例,经核实后最大年龄为60岁,最小年龄为21岁,中位年龄统计后为(4869士633)岁。B组患者中,男性患者、女性患者分别为20例、14例,经核实后最大年龄为61岁,最小年龄为20岁,中位年龄统计后为(4799士654)岁。C组健康人群中,男性、女性分别为24例、10例,经核实后最大年龄为62岁,最小年龄为22岁,中位年龄统计后为(4866士599)岁。在统计软件SPSS190中将A组、B组和C组受检人员的基本信息输入,组间差异呈P>005,则说明数据结果统计学意义未产生。
12具体流程所有抑郁症患者均使用抗抑郁类药物,5-羟色胺再摄取抑制剂,共进行6周的治疗,治疗一周时需将药物剂量适当增加,在此期间不得服用其他抗精神病药物。若患者的睡眠质量较差,可予以苯二氮卓类药物。抗抑郁类药物包括:氟西汀,使用剂量为20mg,帕罗西汀,药物使用剂量为20mg,舍曲林,药物使用剂量为50mg,在上述药物基础上与氟伏沙明、西酞普兰联合使用[2]。
所有受检人员均接受持续性操作测验,利用视觉单目标持续性注意测验,屏幕背景以灰色为主,随机出现不同颜色,如:红、黄、绿、白和黑,字符呈现时间和间隔时间分别为200ms、1300ms,在此期间要求检查人员看到红色“+”字时则按空格键。, http://www.100md.com(李方 闫斌)
【关键词】首发与复发抑郁症;持续性操作测验;结果分析
【中圖分类号】R749.4+1
【文献标志码】B
, 百拇医药
【文章编号】1005-0019(2018)07-020-01
Abstract Objective:To analyze the results of continuous operation test for patients with primary and recurrent depression.Methods: 68 patients with inpatient depression who were admitted to our hospital between July 2016 and August 2017 were divided into two groups, namely, group A(N = 34) and group B(N = 34), according to the starting point and recurrence. Then 34 healthy people were admitted to the hospital in the same period. It was set to group C, group A and group B patients received antidepressant treatment, and then all the subjects were tested using the HAMD scale and continuous operation tests, and the results were summarized.Results: Compared with HAMD scores in group A and B patients, the former improved better than the latter, and the data between groups confirmed that the difference was P 005, which was statistically significant. In addition, the results of the continuous operation test in group A patients and the C group were P > 005, and the results of the continuous operation test in group B patients and the C group were P 005, which was statistically significant. Conclusion: The patients with recurrent depression suffered more serious damage and had longer recovery.
, 百拇医药
在精神科疾病中抑郁症较为常见,其不仅会发生情感症状,同时会损害认知功能,即使治愈后也难以将认知功能恢复至最佳状态。据有关资料显示,抑郁症认知功能会受到诸多因素的影响,如:病情和发作次数,就复发抑郁症患者而言,其认知损害更为显著,同时会增加恢复难度[1]。为此,此研究选择我院近一年(2016年7月至2017年8月)收治的住院抑郁症患者68例,对其实施持续性操作测验得到价值进行探究。
1对象与方法
11基础信息此次研究抽取的住院抑郁症患者68例,收治时间为2016年7月至2017年8月。将所有患者依据首发和复发均分A组(n=34)和B组(n=34),之后选取同期入院的健康人群34例,将其设为C组。A组患者中,男性患者、女性患者分别为22例、12例,经核实后最大年龄为60岁,最小年龄为21岁,中位年龄统计后为(4869士633)岁。B组患者中,男性患者、女性患者分别为20例、14例,经核实后最大年龄为61岁,最小年龄为20岁,中位年龄统计后为(4799士654)岁。C组健康人群中,男性、女性分别为24例、10例,经核实后最大年龄为62岁,最小年龄为22岁,中位年龄统计后为(4866士599)岁。在统计软件SPSS190中将A组、B组和C组受检人员的基本信息输入,组间差异呈P>005,则说明数据结果统计学意义未产生。
12具体流程所有抑郁症患者均使用抗抑郁类药物,5-羟色胺再摄取抑制剂,共进行6周的治疗,治疗一周时需将药物剂量适当增加,在此期间不得服用其他抗精神病药物。若患者的睡眠质量较差,可予以苯二氮卓类药物。抗抑郁类药物包括:氟西汀,使用剂量为20mg,帕罗西汀,药物使用剂量为20mg,舍曲林,药物使用剂量为50mg,在上述药物基础上与氟伏沙明、西酞普兰联合使用[2]。
所有受检人员均接受持续性操作测验,利用视觉单目标持续性注意测验,屏幕背景以灰色为主,随机出现不同颜色,如:红、黄、绿、白和黑,字符呈现时间和间隔时间分别为200ms、1300ms,在此期间要求检查人员看到红色“+”字时则按空格键。, http://www.100md.com(李方 闫斌)
参见:首页 > 保健版 > 心灵空间 > 抑郁症