蛋白多糖在遗传性多发性骨软骨瘤形成中的重要作用研究(1)
【摘 要】目的：分析蛋白多糖在遗传性多发性骨软骨瘤形成中的重要作用。方法：研究对象为遗传性多发性骨软骨瘤患者例数50例作为观察组，使用免疫组织化学方法对蛋白多糖表达实施检测，再选取50例患者的正常软骨作为对照组，患者收取时间在2015年2月1日到2016年2月10日，对两组患者检测结果进行分析和比较。结果：在对照组正常软骨组织中蛋白多糖主要表达在细胞膜周边基质和软骨细胞膜表面，其染色很深，而在观察组肿瘤软骨组织中蛋白多糖表达主要集中在人体细胞膜内侧，细胞外基质中和细胞膜表面表达显著减少。结论：蛋白多糖侧链硫酸肝素链和蛋白多糖表达改变，易导致多发性骨软骨瘤形成，由此提示蛋白多糖在遗传性多发性骨软骨瘤形成中具有十分重要的作用。
【关键词】蛋白多糖；遗传性多发性骨软骨瘤；重要作用；研究
Abstract：Objective To analyze the important role of proteoglycans in the formation of hereditary multiple osteochondroma. METHODS： A total of 50 patients with hereditary multiple osteochondroma were enrolled in the study. The expression of proteoglycan was detected by immunohistochemistry. The normal cartilage of 50 patients was selected as the control group. The patient was charged in 2015. From February 1st to February 10th ......
您现在查看是摘要页，全文长 3989 字符。
【关键词】蛋白多糖；遗传性多发性骨软骨瘤；重要作用；研究
Abstract：Objective To analyze the important role of proteoglycans in the formation of hereditary multiple osteochondroma. METHODS： A total of 50 patients with hereditary multiple osteochondroma were enrolled in the study. The expression of proteoglycan was detected by immunohistochemistry. The normal cartilage of 50 patients was selected as the control group. The patient was charged in 2015. From February 1st to February 10th ......
您现在查看是摘要页，全文长 3989 字符。