【摘 要】目的：探讨肿瘤标志物在降结肠多形性横纹肌肉瘤术后复发诊断及疗效判断价值。方法：对我们诊治的1例降结肠多形性横纹肌肉瘤术后复发转移患者进行阿帕替尼治疗及化疗，动态监测肿瘤标志物，结合CT判断病情变化结果：本例治疗前血清肿瘤标志物NSE明显升高，阿帕替尼治疗后NSE逐渐下降，CT评价效果PR，但治疗9月后NSE逐渐升高直至死亡，复查CT提示PD。结论：多形性横纹肌肉瘤术后容易复发及转移，通过对NSE的动态监测，提示NSE有助于多形性横纹肌肉瘤患者病情监测、评价疗效、判断预后。

    【关键词】降结肠；多形性横纹肌肉瘤；血清肿瘤标志物NSE；阿帕替尼

    Abstract：Objective To Explore the value of tumor markers in the diagnosis and treatment of recurrence of polymorphic rhabdomyosarcoma of descending colon after operation.Method：A case of polymorphic rhabdomyosarcoma of the descending colon who had recurrence and metastasis after operation was treated with apatinib and treated with chemotherapy. Tumor markers were monitored dynamically and the changes of the disease were judged by CT.Results：The serum tumor marker NSE in this case increased significantly before treatment ......