生长抑素、奥美拉唑联合治疗急性胰腺炎的疗效及对患者血清炎症因子水平的影响分析(1)
【摘 要】目的：探究在急性胰腺炎治疗过程中，应用生长抑素、奥美拉唑联合治疗的效果，以及对患者血清炎症因子水平的影响。方法：选择近三年我院收治的300例急性胰腺炎患者作为研究对象，按照患者的入院顺序将其分为对照组(生长抑素治疗)和观察组(生长抑素、奥美拉唑联合治疗)；分别治疗后观察两组效果，以及患者的血清炎症因子水平，并实施组间对比。结果：两组患者治疗前血清炎症因子水平相近，分组治疗后均为观察组显著改善，观察组的各项异常恢复时间快于对照组，且观察组治疗有效率为92.00%，高于对照组的75.67%，组间对比差异均具有统计学意义(P<0.05)。结论：将生长抑素、奥美拉唑联合应用于急性胰腺炎治疗中，可帮助患者相关炎性治疗快速恢复，改善患者临床症状并提高最终治疗效果，因此该方法具有推广应用价值。
【关键词】急性胰腺炎；生长抑素；奥美拉唑；血清炎症因子水平
Effect of somatostatin and omeprazole on acute pancreatitis and its effect on serum inflammatory factor level
Du Yu-xiao(Chongqing tongnan district people's hospital 402660)
Abstract：Objective To investigate the effect of somatostatin combined with omeprazole in the treatment of acute pancreatitis and the effect of somatostatin and omeprazole on serum inflammatory factors.Methods： 300 patients with acute pancreatitis were divided into control group (somatostatin treatment) and observation group (somatostatin combined with omeprazole) according to the order of admission.After treatment， the effect of two groups and the level of serum inflammatory factors were observed and compared between the two groups.Results： the levels of serum inflammatory cytokines in the two groups were similar before treatment， and were significantly changed in the observation group after treatment.The time of abnormal recovery in the observation group was faster than that in the control group， and the effective rate of treatment in the observation group was 92.00， which was higher than that in the control group (75.67g).The difference between the two groups was statistically significant (P < 0.05).Conclusion： the combination of somatostatin and omeprazole in the treatment of acute pancreatitis can help the patients recover quickly， improve the clinical symptoms and improve the final therapeutic effect， so this method has the value of popularization and application.
Key words： acute pancreatitis； somatostatin； omeprazole； serum inflammatory factor level
【中圖分类号】R576 【文献标识码】A 【文章编号】1005-0019(2019)08-00-01
急性胰腺炎属于临床常见疾病，其主要是多种原因的作用使得患者胰酶在胰腺内被激活，导致胰腺组织出现水肿、出血或坏死性炎性反应情况，在未及时治疗的情况下可能导致其发展为多器官功能衰竭现象，危及患者的生命安全，因此一旦确诊后需要对患者开展有效治疗。目前临床可应用于急性胰腺炎的治疗方法较多，本次研究主要分析生长抑素、奥美拉唑联合治疗的效果，目的在于总结经验为相关治疗工作的开展构建新的思路，现将本次研究详情做出整理报道，具体如下。
1 资料和方法
1.1 一般资料
将2015年3月到2018年3月作为本次研究时间段，以上述时间段内选择我院收治的300例急性胰腺炎患者作为研究对象，按照患者的入院顺序将其分为对照组(150例)和观察组(150例)。
两组患者的诊断标准：符合世界卫生组织制定的《急性胰腺炎诊治指南》中关于急性胰腺炎的诊断标准，即患者表现为持续的腹痛现象，对其实施血清淀粉酶检查可见其活性超过正常值上限，影像学检查则可见患者的胰腺形态存在一定变化或无显著变化。, http://www.100md.com(杜雨潇)
【关键词】急性胰腺炎；生长抑素；奥美拉唑；血清炎症因子水平
Effect of somatostatin and omeprazole on acute pancreatitis and its effect on serum inflammatory factor level
Du Yu-xiao(Chongqing tongnan district people's hospital 402660)
Abstract：Objective To investigate the effect of somatostatin combined with omeprazole in the treatment of acute pancreatitis and the effect of somatostatin and omeprazole on serum inflammatory factors.Methods： 300 patients with acute pancreatitis were divided into control group (somatostatin treatment) and observation group (somatostatin combined with omeprazole) according to the order of admission.After treatment， the effect of two groups and the level of serum inflammatory factors were observed and compared between the two groups.Results： the levels of serum inflammatory cytokines in the two groups were similar before treatment， and were significantly changed in the observation group after treatment.The time of abnormal recovery in the observation group was faster than that in the control group， and the effective rate of treatment in the observation group was 92.00， which was higher than that in the control group (75.67g).The difference between the two groups was statistically significant (P < 0.05).Conclusion： the combination of somatostatin and omeprazole in the treatment of acute pancreatitis can help the patients recover quickly， improve the clinical symptoms and improve the final therapeutic effect， so this method has the value of popularization and application.
Key words： acute pancreatitis； somatostatin； omeprazole； serum inflammatory factor level
【中圖分类号】R576 【文献标识码】A 【文章编号】1005-0019(2019)08-00-01
急性胰腺炎属于临床常见疾病，其主要是多种原因的作用使得患者胰酶在胰腺内被激活，导致胰腺组织出现水肿、出血或坏死性炎性反应情况，在未及时治疗的情况下可能导致其发展为多器官功能衰竭现象，危及患者的生命安全，因此一旦确诊后需要对患者开展有效治疗。目前临床可应用于急性胰腺炎的治疗方法较多，本次研究主要分析生长抑素、奥美拉唑联合治疗的效果，目的在于总结经验为相关治疗工作的开展构建新的思路，现将本次研究详情做出整理报道，具体如下。
1 资料和方法
1.1 一般资料
将2015年3月到2018年3月作为本次研究时间段，以上述时间段内选择我院收治的300例急性胰腺炎患者作为研究对象，按照患者的入院顺序将其分为对照组(150例)和观察组(150例)。
两组患者的诊断标准：符合世界卫生组织制定的《急性胰腺炎诊治指南》中关于急性胰腺炎的诊断标准，即患者表现为持续的腹痛现象，对其实施血清淀粉酶检查可见其活性超过正常值上限，影像学检查则可见患者的胰腺形态存在一定变化或无显著变化。, http://www.100md.com(杜雨潇)