【摘要】目的 探讨克林霉素致不良反应发生的一般规律，为临床合理用药提供参考。 方法 对我院2009年1月-2011年1月住院病例中12例克林霉素不良反应报告进行分类统计、分析。结果 ADR临床表现以皮肤及附件损害为最多，其次为泌尿系统损害及过敏性休克。 结论 克林霉素的使用应严格掌握用药指征，加强用药监测;避免不必要的联合用药及预防性用药，重视药物相互作用诱发或加重ADR发生的可能性，以减少或避免ADR对患者的危害。

    【关键词】克林霉素 不良反应 安全用药

    中图分类号：R994.11文献标识码：A文章编号：1005-0515(2011)3-039-02

    Clindamycin 12 cases of clinical adverse reaction reports

    YANGLiping

    (Baoshan City, Yunnan Province, the Second People's Hospital Department of Pharmacy, Yunnan Baoshan 678000)

    【Abstract】Objective To investigate the incidence of adverse reactions caused by clindamycin general law, provide a reference for the clinical use of drugs. MethodsThe hospital in January 2009 -2011 on Jan. 12 cases of hospitalized cases of clindamycin adverse reaction reports classified statistical analysis. Results ADR clinical manifestations of damage to the skin and its appendages, followed by urinary system damage and allergic shock. Conclusion The use of clindamycin treatment indications should be strictly controlled to enhance drug monitoring; to avoid unnecessary and preventive drug combination, attention to drug interactions induced or exacerbated by the likelihood of ADR, ADR to reduce or prevent the patient hazards. ......