【摘要】近几年来国内外通过分析接受减肥手术的肥胖患者发现，减肥手术在减轻体重的同时也使肥胖患者的糖尿病得到了很大程度的缓解。除了体重减轻、摄食减少外，肠促胰岛素(GIP，GLP-1)分泌的变化可能是其术后糖尿病缓解的主要原因。本文将对减肥手术治疗2型糖尿病中肠促胰岛素可能发挥的作用作一简单综述。

    【关键词】减肥手术 2型糖尿病 GIP GLP-1

    中图分类号：R587.1文献标识码：B文章编号：1005-0515(2011)3-318-02

    【Abstract】In recent years,doctors at home and abroad find,when they analyse the patients with morbid obesity undergoing bariatic surgery,that the surgery not only reduces the body mass but also relieves the diabetes mellitus of the patients. Except for the reduction of body mass and food intake,the change of Incretin(GIP,GLP-1) secretion may be the main reason for the relief.Here,The article will review the role the Incretin play in therapy of type 2 diabetes mellitus after bariatic surgery.

    【Key Words】Bariatric surgery Type 2 diabetes mellitus GIP GLP-1

    2型糖尿病是以胰岛素抵抗或(和)胰岛索分泌缺陷为主要特征的复杂代谢性疾 ......