酒精性脂肪肝的临床观察研究
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【摘要】目的 对酒精性脂肪肝患者进行临床观察分析，探讨治疗酒精性脂肪肝的方法。方法 选取我院2009年12月～2010年12月被确诊为酒精性脂肪肝的患者128 例，随机分为对照组和观察组各64例。对照组患者给予口服己酮可可碱肠溶片，观察组患者在对照组治疗基础上加服多维生素片，4周为一个疗程。结果 治疗后两组患者的血清谷丙转氨酶、谷草转氨酶、胆固醇、甘油三酯等指标均有不同程度的改善。观察组患者的改善程度明显优于对照组，差异有统计学意义(p<0.05)。治疗后对照组患者显效者25例，有效者22例，无效者17例，总有效率73.4%。观察组患者显效者27例，有效者29例，无效者8例，总有效率87.5%。观察组总有效率明显高于对照组，差异有统计学意义(p<0.05)。结论 己酮可可碱肠溶片联合多维生素片治疗酒精性脂肪肝，可以取得较满意的疗效，值得临床推广。
【关键词】酒精性脂肪肝 己酮可可碱 维生素
中图分类号：R575.5 文献标识码：A 文章编号：1005-0515(2011)5-013-02
Alcoholic fatty liver disease clinical study
MAO Ying
(Jianyang City, Sichuan Province, Sichuan Province People's Hospital 641400 Jianyang )
【Abstract】Objective alcoholic fatty liver patients with clinical observation and analysis of the treatment method of alcoholic fatty liver. Methods in our hospital in December 2009 ~ December 2010 was diagnosed with fatty liver alcohol 128 patients were randomly divided into control group and observation group of 64 cases. The control group were treated with oral pentoxifylline enteric-coated tablets were observed in the control group patients on the basis of multi-vitamin tablets plus service, 4 weeks for a course of treatment. Results After treatment, the serum alanine aminotransferase, aspartate aminotransferase, cholesterol, triglycerides and other indicators have improved to varying degrees. Degree of improvement observed in patients than the control group, the difference was statistically significant (p <0.05). The control group after treatment, 25 cases were markedly effective in 22 cases, ineffective in 17 cases, the total efficiency of 73.4%. Observation group, 27 cases were markedly effective in 29 cases, ineffective in 8 patients, 87.5%. The total effective observation group was significantly higher, the difference was statistically significant (p <0.05). Conclusion Pentoxifylline joint multi-vitamin tablets enteric coated tablet treatment of alcoholic fatty liver can be achieved more satisfactory results, it is worth to be popularized.
近年来随着人们生活水平的提高，酒精性脂肪肝(alcoholic fatty liver disease，AFLD)的发生率也逐年递增，如不及时采取措施很可能发展为酒精性肝炎、肝纤维化甚至肝硬化[1]。我院采用己酮可可碱肠溶片联合多维生素片治疗酒精性脂肪肝，取得了较满意的疗效，现将资料整理如下。
1 资料与方法
1.1 一般资料 ......
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