2007-2009年阿坝州麻疹疑似病例血清IgM抗体检测结果分析(1)
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【摘要】目的 了解阿坝州2007年-2009年麻疹疑似病例血标本采集率，实验室确诊率，探讨阿坝州麻疹发病的流行病学特点，为进一步控制和消除麻疹提供科学依据。方法 对2007-2009年收集的435份麻疹疑似病例早期血清标本，采用抗体捕捉酶联免疫吸附实验(ELISA)检测麻疹IgM抗体，结合流行病学资料进行分析。结果 2007年-2009年阿坝州共报告麻疹疑似病例824例，采集血标本435份，随着麻疹监测工作方案的开展和实施，标本采集逐年提高(2007年37.7%，2009年85.0%)。麻疹抗体阳性 236 例，实验室确诊率 53.6 %。全年每月均有发病，主要集中在2-7月为发病高峰。15岁以下年龄组为麻疹的高发年龄组，20-30岁年龄组有发病增多的趋势。对麻疹病例免疫接种史分析，有明确麻疹疫苗免疫史的共有 41例，占总病例数的 25.3%，无免疫史的 114例，占总病例数的48.9%，免疫史不详81例，占总病例数的27.6 %。结论 提高疑似麻疹病例的血清标本采集率，及时对疑似病例进行确诊。加强室内质控，提高检测结果的准确性。进一步加强对预防接种工作的管理，尤其是对免疫空白进行强化免疫，以达到2012年基本消除麻疹的目标。在较大年龄组中开展麻疹疫苗的复种或强化免疫工作。
【关键词】麻疹 疑似病例 IgM抗体 流行病
中图分类号：R446.3 文献标识码：A 文章编号：1005-0515(2012)2-025-02
Analysis of detection result of IgM serum antibody of suspected cases of measles in A’Ba from 2007 to 2009
YANG Huiqiong ZHOU Yan ZHANG Zhang
( Sichuan A’Ba Center for Disease Control and Prevention, Sichuan Ma’erkang，624000，China )
【Abstract】Objective To know the A’Ba from 2007 to 2009 Measles Suspected Cases of blood specimen collection rate, laboratory diagnosis rate, inquire into the A’Ba Measles Epidemiological characteristics, in order to further control and eliminate measles and provide a scientific basis. Methods Use antigen capture enzyme-linked immunosorbent assay ( ELISA ) for detection of measles IgM antibody, from the early serum specimens of 435 suspected measles cases collected from 2007 to 2009, combine with epidemiological data and analyse. Results From2007 to 2009，a total of 824 measles cases were reported in A’Ba , 435 blood specimens were collected from suspected cases, with program of the measles detection development and implementation, specimen collection increased year by year (2007 37.7%, 2009 85% ). 236 cases were measles antibody positive , inlaboratory diagnosis rate was53.6%. There were incidences in each month all the year , the incidence peak mainly concentrated in the 2-7 months . The under 15 age group was measles high-risk group, 20-30 age group has the trend of increasing incidence ......
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