早期灌肠对早产儿黄疸的影响(1)
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【摘要】 目的 探讨早期使用开塞露灌肠对早产儿黄疸的影响。 方法 将50例早产儿随机分为治疗组25例和对照组25例,治疗组用10ml注射器抽取开塞露2ml/kg,加等量生理盐水,用消毒8号导尿管轻轻插入肛门内约2—3cm,然后把抽取好的开塞露经导尿管缓慢注入肛门,注射完后停留2分钟再拔出尿管;对照组不用开塞露,按常规护理。观察两组早产儿胎便排完所需时间、经皮胆红素值。 结果 治疗组胎便排完所需时间短,经皮胆红素值低,黄疸发病率明显低于对照组,两组差异有极显著意义(P<0.01)。 结论 对早产儿黄疸进行早期干预,能有效降低早产儿黄疸的发病率,进而减少胆红素脑病的发生机率,从而提高围产儿生命质量。
【关键词】开塞露灌肠早产儿黄疸
【中图分类号】R722.17 【文献标识码】 B 【文章编号】1005-0515(2010)008-002-03
Early enema on the impact of premature infants with jaundice
Helping women and children of Guangdong Province, Maihaiyan 527300
[Abstract] Objective:On the early use of glycerine enema on the impact of premature infants with jaundice. Methods: Random 50 premature is divided into 25 cases of treatment group and a control group of 25 cases, treatment of used-amoxycillin injector glycenine enema 2ml/kg, with equal amounts of normal saline, disinfecting mountains(08) catheter insertion lightly about 2-3 cm, and then to take samples of good glycenine enema through the catheter slow after injection inject anusof, aroundafter 2 minutes and pull out the tube; a control group without glycenine enema ,routine care. Observation of two sets of fetal expulsion in premature infants to finish the required time, precutaneous cholerythrin value.Results: Treatment group meconium row required only for short periods when you are finished, with precutaneous cholerythrin, janndice incidence significantly lower than the control group, there is a difference between the two groups significant (P0.01). Conclusion: To premature janndice for an effective early intervention, asehnoune choloplania, which in turn reduce the incidence of encephalopathy occur, thereby enhancing the quality of life of perinatals.
[Key Word] Glycenine enemaClysisPrematureJaundice
早产儿由于肠肝循环较足月儿增加,黄疸程度重,当经皮胆红素值>256.5μmol/L(26.5UI)就可能发生胆红素脑病,且血脑屏障尚未完善,如缺氧、酸中毒等而开放,使胆红素易通过血脑屏障,未结合胆红素对脑细胞有毒性作用,此时经皮胆红素值>171.0μmol/L(20.5UI)也有发生胆红素脑病的可能[1]。为了减少早产儿胆红素脑病发生机率,以往当经皮胆红素值>171.0μmol/L(20.5UI)常采用蓝光照射预防,但蓝光照射副作用多。有研究显示灌肠预防新生儿胆红素脑病效果显著[2,3]。早产儿胆红素脑病常发生于生后10天内,我科于2007年9月~2008年12月对收治的50例单纯早产儿,将其随机分为治疗组和对照组,治疗组予灌肠干预以促进胎便排出,观察10天。早产儿黄疸的早期预防和治疗是降低新生儿黄疸发病率、减轻病情、缩短病程的关键 ......
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