【摘要】 目的 探讨盐酸文拉法辛对躯体形式障碍的临床疗效及副反应。 方法 采用随机分组的方法，将114例躯体形式障碍患者分为文拉法辛组57例，丙米嗪组57例，治疗8周，用 HAMD和TESS评定疗效和副反应。结果 文拉法辛组与丙米嗪组对躯体形式障 碍的起效时间有显著性差异(P<0.05)，副反应方面有显著性差异(P<0.01)。 结论 SNRI与TCAs之间比较对躯体形式障碍有效、安全、起效快，值 得临床应用。

    【关键词】 盐酸文拉法辛；丙米嗪；躯体形式障碍；汉密尔顿抑郁量表；副反应 量表

    A Comparative Study on Venlafaxine and Impramine in the Treatment of SomatoformDisorders. Shan Jing, Zhao Yun, Jia Huizhen, et al. Harison Internationa l Peace Hospital of Hengshui, Hengshui 053000, P.R.China

    【Abstract】 Objective To study the clinical effects and side effectsof venlafaxine in treatment of somatoform disorders. Methods 114patient with somatof orm disorders were randomly divided into venlafaxine (57 patients) and impramine(57 patients) group, and treated for 8 weeks. The clinical effects and side eff ects were tested with HAMD and TESS. Results The clinical effec t of venlafaxine were similar to impramine. The paroxetine had less side effectsthan impramine (P[1] ......