急性脑梗死早期尿激酶静脉溶栓治疗的临床分析(1)
 |
| 第1页 |
参见附件(2356KB，3页)。
【中图分类号】R743.3【文献标识码】A【文章编号】1005-2720(2009)06-0144-03
【摘要】目的：探讨急性脑梗死早期应用尿激酶静脉溶栓治疗的疗效及安全性。方法：2002年1月~2008年6月来我院就诊的急性脑梗死76例患者随机分为治疗组38例，对照组38例。治疗组6h内给予尿激酶100万U加入生理盐水100ml，静脉滴注，以后静滴银杏达莫20ml(溶于生理盐水250ml)，半小时滴完。溶栓前后应用脑保护剂治疗。对照组给予银杏达莫20ml静脉滴注，并同时应用脑保护剂治疗。两组常规治疗一致。在治疗24h、7d、21d分别进行临床疗效评定。结果：治疗组痊愈率、神经功能缺损恢复的程度和安全性均明显优于对照组(P<0.01)。结论：急性脑梗死早期尿激酶溶栓治疗能显著提高急性脑梗死的治愈率，降低病死率，减少并发症和降低了致残程度，且安全、可靠，适宜在基层医院推广应用。
【关键词】急性脑梗死：尿激酶；静脉溶栓；脑保护剂
Clinical analysis of early acute cerebral infarction with urokinase intravenous thrombolytic therapy.Jiang Chengyang.(Department of Medicine，Lishui hospital of Nanhai district，Foshan，Guangdong 528244 China)
【Abstract】 Objective：To investigate the efficacy and safety of the early use of acute cerebral infarction with urokinase intravenous thrombolytic therapy.Methods：From January 2002 to June 2008，came to our hospital for treatment of 76 cases of acute cerebral infarction were randomly divided into treatment group for 38 cases，38 cases of the control group.6h treatment group within the class to 1，000，000U urokinase add saline 100ml，intravenous drip，after the intravenous Yinxingdamo 20ml(dissolved in normal saline 250ml)，half an hour after drop.Before and after thrombolytic treatment of cerebral protective agent.Control group given Yinxingdamo 20ml intravenous drip，while the application of the treatment of brain protective agent.Conventional treatment of the two groups agreed.In the treatment of 24h，7d，21d，respectively，to assess clinical efficacy.Results：In the treatment group cure rate of recovery of neurological deficit and safety were significantly better than the control group(P<0.01).Conclusion：The early acute cerebral infarction with urokinase thrombolytic therapy can significantly improve the cure rate of acute cerebral infarction to reduce mortality，reduce complications and reduce the extent of disabilities，and the safe，reliable，and suitable for application at the grass-roots hospital.
【Key Words】 Acute cerebral infarction；Urokinase；Intravenous thrombolysis；Cerebral protective agent
脑梗死是一个以发病急、神经功能缺失为特点的脑血管病。急性脑梗死(acute cerebral infarction，ACI)的神经元损伤是造成神经功能缺损，导致病残，影响生活质量的重要原因[1] ......
您现在查看是摘要介绍页，详见PDF附件(2356KB，3页)。